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The value and therapeutic potential of medicinal plants as molecular sources has been demonstrated throughout history and remains an important resource for identifying novel drug leads. A major asset in medicinal plant drug discovery is the presence of ethnopharmacological information that provides clues to the therapeutic efficacy of compounds in humans. With the coming of an aging society, neurodegenerative conditions have arguably become the most dreaded maladies of the elderly. The latest idea is that some aspects of the aging process can be reversed at a younger age if the brain is malleable. If this idea is realized, it may also be possible to slow or reverse neurodegeneration and cognitive impairment. Natural medicines display promising neuroprotective and neuroreparatived properties in neurological diseases.
Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of omics-driven advances across different aspects of exercise and sports physiology, biochemistry, sports medicine, psychology, anthropology, and sports nutrition; and highlighting the opportunities towards advance personalized training and athlete health management. More than 70 international experts from 14 countries have discussed key exercise and sport-related themes through the prism of genomics, epigenomics, transcriptomics, proteomics, metabolomics, telomere biology, talent in sport, individual differences in response to regular physical activi...
La Fibromialgia è considerata una sindrome da sensibilizzazione centrale che si manifesta prevalentemente con dolore a carico dell'apparato muscolo scheletrico. Nella pubblicazione sono esposti diversi argomenti, come la descrizione della sindrome fibromialgica, l'insonnia, la correlazione dell'infiammazione con il dolore, l'associazione della Fibromialgia con l'acidosi della matrice extracellulare, il tessuto adiposo fattore scatenante l'infiammazione e il dolore, le infezioni virali persistenti, l'approfondimento del microbiota, della disbiosi e permeabilità intestinale e della potenzialità dei probiotici. Tuttavia, si è evidenziata la correlazione tra il nesso causale della Fibromialg...
Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox home...
The management of chronic pain in companion animals is an area in which there is a significant therapeutic void. In many cases professionals are unaware of the appropriate approach to manage chronic pain, despite the wide range of pharmacological, surgical and physical therapeutic options that act directly on the pain pathways. Recent discoveries in the area of pain pathways have opened many avenues for the management of chronic pain. The goal of this book is to present this new knowledge in the context of the small animal clinic. -- back cover.