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Proteomics
  • Language: en
  • Pages: 414

Proteomics

  • Type: Book
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  • Published: 2023-02-14
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  • Publisher: Elsevier

Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, an...

Black Seeds (Nigella sativa)
  • Language: en
  • Pages: 488

Black Seeds (Nigella sativa)

  • Type: Book
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  • Published: 2021-09-23
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  • Publisher: Elsevier

Black Seeds (Nigella sativa) is a comprehensive resource covering all aspects of this medicinal plant, well-known for its positive effects in many human ailments. It has been used to promote health and fight diseases, and has been found to have antioxidant, antihypertensive, anti-diabetic, anti-inflammatory, and analgesic effects. It has also been known to have antimicrobial, anticancer, neuro-protectant, cardio protectant, immunomodulator, hepatic protectant characteristics. Thymoquinone, the active compound of the plant, also exhibits these protective qualities against many disorders. This book summarizes the effect of this plant on all the organ systems of the body. Black Seeds (Nigella s...

Immunogenetics: A Molecular and Clinical Overview
  • Language: en
  • Pages: 412

Immunogenetics: A Molecular and Clinical Overview

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An addition...

Immunogenetics: A Molecular and Clinical Overview
  • Language: en
  • Pages: 427

Immunogenetics: A Molecular and Clinical Overview

Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic. Contains exclusive information about global research on immunogenetics Provides a solid foundation to researchers wanting to work on immunogenetics and their application in different autoimmune, viral and infectious diseases Delivers information in a meticulous, attractive manner using pictures, illustrations and tables Gives insights into immunogenetics and its utility in therapeutics

Pharmacogenomics
  • Language: en
  • Pages: 392

Pharmacogenomics

  • Type: Book
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  • Published: 2023-06-13
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  • Publisher: Elsevier

Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, p...

Biological Insights of Multi-Omics Technologies in Human Diseases
  • Language: en
  • Pages: 420

Biological Insights of Multi-Omics Technologies in Human Diseases

  • Type: Book
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  • Published: 2024-06-28
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  • Publisher: Elsevier

"Biological Insights of Multi-Omics Technologies in Human Diseases ́ provides detailed information about the basics of multi-omic technologies including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharm...

Dihydropyrimidinones as Potent Anticancer Agents
  • Language: en
  • Pages: 275

Dihydropyrimidinones as Potent Anticancer Agents

  • Type: Book
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  • Published: 2023-08-15
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  • Publisher: Elsevier

Dihydropyrimidinones as Potent Anticancer Agents gives readers a unique update on scientific knowledge, accomplishments and recent advances in the medicinal chemistry of dihydropyrimidinones in cancer treatment. Dihydropyrimidinones are known to be active scaffold and have been reported to show some exceptional results with regards to malignancies. With ever increasing knowledge and information about synthesis, pharmacology and other aspects of dihydropyrimidinones, there is need to document such information in one place. Since the field of medicinal chemistry is dynamic, with new emerging trends, it provides readily available updated information on chemistry and pharmacology aspects of dihydropyrimidinones in cancer. This book covers everything about dihydropyrimidinones from synthesis, derivatives, mode of action and potential therapeutic targets. It will also provide insights about the clinical trials and way forward in cancer research of dihydropyrimidinones. Covers dihydropyrimidinones synthesis, derivatives and mode of action Includes recent advances in dihydropyrimidinones for cancer treatment Highlights potential therapeutic targetsa

Immunotoxicogenomics
  • Language: en

Immunotoxicogenomics

  • Type: Book
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  • Published: 2024-03-01
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  • Publisher: Elsevier

Immunotoxicogenomics: A Multidisciplinary Approach in Systems Toxicology provides broad coverage to diverse aspects of immunotoxicogenomics. The book covers the major mechanisms and effects of toxic substances on the immune system and on the regulation of gene expression. This includes the aims, opportunities, clinical applications, recent developments, emerging and future trends in immunotoxicogenomics.The book starts off with a discussion of the systemic approach to the study of toxicants. It also looks at the current genomic tools used to assess immunotoxicity and the systems biology methods used in immuno-toxicogenomics. Other topics include genomic expression profiling, the use of gene ...

Therapeutic Applications of Honey and its Phytochemicals
  • Language: en
  • Pages: 451

Therapeutic Applications of Honey and its Phytochemicals

Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals. It is reported to be beneficial in the treatment of various diseases, such as those affecting the respiratory, cardiovascular, gastrointestinal, and nervous systems, as well as diabetes mellitus and certain types of cancers; however, there is limited literature describing the use of honey in modern medicine. This book provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.

Immunogenetics: A Molecular and Clinical Overview
  • Language: en

Immunogenetics: A Molecular and Clinical Overview

Reproductive Immunogenetics: A Molecular and Clinical Overview: Immunogenetic Factors and Signaling Pathways in Recurrent Miscarriage, vol. 4 provides an overview of the scientific knowledge, achievements and findings in the field of the immunogenetic factors and the signaling pathways that could lead to recurrent pregnancy loss. With a strong focus on the role of signaling factors in recurrent pregnancy loss, the book also examines the predictors, etiology and diagnosis of recurrent pregnancy loss. In 17 chapters the book describes the roles of several different signaling pathways are the role of JLA and microRNAs in recurrent pregnancy loss. Several chapters are dedicated to the role autoimmune antibodies play in recurrent pregnancy loss. Reproductive Immunogenetics: A Molecular and Clinical Overview: Immunogenetic Factors and Signaling Pathways in Recurrent Miscarriage, vol. 4 is a valuable resource for health professionals, scientists and researchers, and all those who wish to broaden their knowledge in the allied field and builds the tremendous interest of researchers in the immune therapeutics that may increase the hope of affected couples for childbearing.