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Emerging Pathogens, An Issue of Clinics in Laboratory Medicine, E-Book
  • Language: en

Emerging Pathogens, An Issue of Clinics in Laboratory Medicine, E-Book

This issue of Clinics in Laboratory Medicine, edited by Drs. Nahed Ismail, A. William Pasculle, and James Snyder, will cover a wide variety of Emerging Pathogens. Topics covered in this issue include, but are not limited to West Nile Virus; Zika Virus; Ebola and Marburg Heamorrhagic Fever; Rift Valley Fever; Carbapenem Resistant Enterobacteriacae; Closteridium Difficuile; and Chikungunya, among others.

Infection and Cancer: Bi-Directorial Interactions
  • Language: en
  • Pages: 408

Infection and Cancer: Bi-Directorial Interactions

  • Type: Book
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  • Published: 2015-11-02
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  • Publisher: Springer

This unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression. Chapters are organized into themed parts, beginning with a look at the historical perspective of human tumor viruses, then aspects and examples of infection-related cancers and cancer-associated infections. The work discusses how cancer- and infection-associated immune responses interact in a bi-directorial fashion and how these interactions may evolve during both disease progression and in respons...

Infection and Cancer: Bi-Directorial Interactions
  • Language: en

Infection and Cancer: Bi-Directorial Interactions

  • Type: Book
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  • Published: 2015
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  • Publisher: Unknown

This unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression. Chapters are organized into themed parts, beginning with a look at the historical perspective of human tumor viruses, then aspects and examples of infection-related cancers and cancer-associated infections. The work discusses how cancer- and infection-associated immune responses interact in a bi-directorial fashion and how these interactions may evolve during both disease progression and in respons...

Cell Encapsulation Technology and Therapeutics
  • Language: en
  • Pages: 457

Cell Encapsulation Technology and Therapeutics

The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept int...

Rediscovering the Immune System as an Integrated Organ
  • Language: en
  • Pages: 288

Rediscovering the Immune System as an Integrated Organ

  • Type: Book
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  • Published: 2016-01-29
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  • Publisher: FriesenPress

The mainstream view of the immune system is concerned with molecular and cellular details resulting in a picture of immense complexity. Many immunologists live with this complexity, hoping that a series of breakthroughs will eventually add up to a greater insight. However, the forest is ignored for the trees and a ‘Systems Approach’ is vital for a better understanding. Peter Bretscher develops here a unique perspective on how the immune system functions as an integrated organ, by taking account of observations and concepts at the ‘level of system’ that are often half forgotten or ignored. A colleague, on reading this book, wrote: “Those who have followed Peter’s work these past 5...

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases
  • Language: en
  • Pages: 560

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases

A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.

Molecular Detection of Human Bacterial Pathogens
  • Language: en
  • Pages: 1258

Molecular Detection of Human Bacterial Pathogens

  • Type: Book
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  • Published: 2011-04-18
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  • Publisher: CRC Press

As more original molecular protocols and subsequent modifications are described in the literature, it has become difficult for those not directly involved in the development of these protocols to know which are most appropriate to adopt for accurate identification of bacterial pathogens. Molecular Detection of Human Bacterial Pathogens addresses th

Endometriosis
  • Language: en
  • Pages: 504

Endometriosis

This book provides an insight into the emerging trends in pathogenesis, diagnosis and management of endometriosis. Key features of the book include overviews of endometriosis; endometrial angiogenesis, stem cells involvement, immunological and hormonal aspects related to the disease pathogenesis; recent research reports on infertility, endometrial receptivity, ovarian cancer and altered gene expression associated with endometriosis; various predictive markers, and imaging modalities including MRI and ultrasound for efficient diagnosis; as well as current non-hormonal and hormonal treatment strategies This book is expected to be a valuable resource for clinicians, scientists and students who would like to have an improved understanding of endometriosis and also appreciate recent research trends associated with this disease.

Molecular Vaccines against Pathogens in the Post-Genomic Era
  • Language: en
  • Pages: 158
Pathogenesis, Diagnostics, Treatments of Mycobacterium tuberculosis and Its co-Infection with HIV or SARS-CoV-2
  • Language: en
  • Pages: 108

Pathogenesis, Diagnostics, Treatments of Mycobacterium tuberculosis and Its co-Infection with HIV or SARS-CoV-2

Mycobacterium tuberculosis is the major cause of tuberculosis (TB) across the globe. Around one-fourth of the world’s population is infected with TB asymptomatically. Longer regimen of anti-TB drugs (longer treatment leading to poor adherence to treatment), interrupted anti-TB drugs treatment (long regimen with incomplete anti-TB treatment), and ineffectiveness of the anti-TB drugs due to the re-emergence of latent TB infections are just a few mechanisms that play a major hindrance to achieving the end of the global TB epidemic by 2035 as WHO plans. The emergence of drug-resistant in Mycobacterium tuberculosis and co-infections with HIV as well as SARS-CoV-2 poses a serious threat to globa...