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The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept int...
The book Immunopathogenesis and Immune-Based Therapy for Selected Autoimmune Disorders is a synthesis work that discusses two main aspects of autoimmunity: Immunopathogenesis and therapeutic approaches essentially based on the immunotherapies. This book deals with different topics on a number of autoimmune disorders, including type 1 diabetes, autoimmune cardiomyopathy, autoimmunity of gastrointestinal tract, systemic sclerosis, and myasthenia gravis. This book will be useful to clinicians, biologists, researchers, teachers, and students who are interested in immunology and immunopathology.
Examines current methods of procuring and preserving the pancreas. Approaches to pancreatic tissue digestion and islet purification, collagenese selection and islet isolation from rodents are discussed.
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L'encapsulation est une technologie de pointe pour l'immobilisation, la protection et la libération contrôlées des principes actifs pour des applications diverses allant du traitement médical à l'agriculture durable, de la cosmétique à l'industrie automobile. L'amélioration des performances, la création de fonctions et propriétés nouvelles, la simplification des procédés qu'autorise la microencapsulation en font une technologie incontournable pour de nombreux développements industriels. L'ouvrage Microencapsulation - Des sciences aux technologies, se veut la compilation de référence francophone permettant tant au néophyte qu'au chercheur confirmé de trouver une information ...