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Although melanoma represents a limited number of cutaneous cancers each year, it remains a significant public health crisis because the metastatic disease is associated with poor survival. The incidence of the disease has increased 200% since 1973 and the median age at diagnosis is 40 years, making it one of the most significant cancers responsible for productive years of life lost. Fortunately, there has been unprecedented progress in the treatment of advanced melanoma, largely through advances in understanding how to manipulate immune responses and target selective genetic mutations in melanoma patients. Clinical benefits to patients with advanced melanoma have been nevertheless limited by...
This book is a complete guide to the evaluation and interpretation of liver biopsy specimens for clinicians, providing the latest techniques and advances in the field. Beginning with an introduction to the structure and function of the ‘normal’ liver, and discussion on situations requiring biopsy, and types of specimen, the following sections describe pathologic variations of liver diseases, ways to identify the changes, and qualitative and quantitative evaluation. The book covers the full spectrum of disorders and diseases that may occur in the liver and includes chapters dedicated to liver transplant pathology, and paediatric liver disease. Current terminologies, grading and staging systems used in liver biopsy, are discussed in detail. High definition slides and images enhance learning, and each chapter concludes with ‘points to remember’ highlighting the key features of the topic. Key Points Complete guide to evaluation and interpretation of liver biopsy specimens Covers the full spectrum of liver disorders and diseases Includes discussion on terminologies, grading, and staging systems Features high definition slides and images, and key learning points
This book is a practical guide to renal biopsy interpretation for trainees in pathology and nephrology. Beginning with an introduction to biopsy, indications and histopathologic evaluation, the following chapters cover biopsy and subsequent diagnosis of different renal diseases. Presented in bullet point format for ease of learning, each chapter begins with an abstract summarising the key points of the topic, and concludes with detailed references for further reading. The text is further enhanced by pathologic photographs and figures to assist understanding. Key points Practical guide to renal biopsy interpretation for trainees Presented in bullet point format for ease of learning Each chapter includes a summary abstract and references for further reading Features pathologic photographs and figures to assist understanding
A gentle introduction to genetic algorithms. Genetic algorithms revisited: mathematical foundations. Computer implementation of a genetic algorithm. Some applications of genetic algorithms. Advanced operators and techniques in genetic search. Introduction to genetics-based machine learning. Applications of genetics-based machine learning. A look back, a glance ahead. A review of combinatorics and elementary probability. Pascal with random number generation for fortran, basic, and cobol programmers. A simple genetic algorithm (SGA) in pascal. A simple classifier system(SCS) in pascal. Partition coefficient transforms for problem-coding analysis.
This book is a complete guide to gastrointestinal diseases and disorders for trainees in gastroenterology. Sixteen sections each cover a different symptom, explaining signs, clinical features, investigation methods, differential diagnosis and treatment. Topics include chronic abdominal pain, anorectal problems, gastrointestinal bleeding, eating disorders, jaundice, abdominal masses, liver failure, and much more. Authored by Consultant Gastroenterologist Her Hsin Tsai from Hull and East Yorkshire Hospitals NHS Trust, this practical text is further enhanced by more than 350 clinical photographs, radiological images, diagrams and tables to assist learning. Key points Complete guide to gastrointestinal diseases and disorders for trainees Covers many different symptoms, their clinical features, investigation, differential diagnosis and treatment Authored by recognised Hull-based Consultant Gastroenterologist Highly illustrated with clinical photographs, radiological images, diagrams and tables
Although melanoma represents a limited number of cutaneous cancers each year, it remains a significant public health crisis because the metastatic disease is associated with poor survival. The incidence of the disease has increased 200% since 1973 and the median age at diagnosis is 40 years, making it one of the most significant cancers responsible for productive years of life lost. Fortunately, there has been unprecedented progress in the treatment of advanced melanoma, largely through advances in understanding how to manipulate immune responses and target selective genetic mutations in melanoma patients. Clinical benefits to patients with advanced melanoma have been nevertheless limited by...
Legumes include many very important crop plants that contribute very critical protein to the diets of both humans and animals around the world. Their unique ability to fix atmospheric nitrogen in association with Rhizobia enriches soil fertility, and establishes the importance of their niche in agriculture. Divided into two volumes, this work presents an up-to-date analysis of in vitro and recombinant DNA technologies for the improvement of grain, forage and tree legumes. Volume 10B presents the current state and future prospects of in vitro regeneration and genetic transformation expression and stability of transgenes modification of traits in almost all the important legumes, for example: soybean; peanut; pea; french bean; chick pea; pigeon pea; cowpea; mung bean; black gram; azuki bean; lentil; Lathyrus; lupinus; Lotus spp; Medicago spp; Trifolium spp; Winged bean; Guar; and tree legumes for their improvement.
Data Science has become a popular field of work today. However a good resource to understand applied Data Science is still missing. In Data Science Uncovering the Reality, a group of IITians unravel how Data Science is done in the industry. They have interviewed Data Science and technology leaders at top companies in India and presented their learnings here. This book will give you honest answers to questions such as: How to build a career in Data Science? How A.I. is used in the world’s most successful companies. How Data Science leaders actually work and the challenges they face.
This new edition is a comprehensive guide to clinical pathology for undergraduate medical students. Divided into three main sections, the text begins with discussion on clinical chemistry and other laboratory tests in the diagnosis and management of disease. Topics include function tests for urinal, renal and liver disorders, tests for diabetes, cerebrospinal fluid tests, and more. Section two covers blood tests for numerous disorders, and the third section discusses blood groups, their compatibility, screening, and transfusion. The second edition has been fully revised to provide the latest advances in the field. New topics in immunology, serology, flow cytometry and immunohistochemistry in...