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This detailed volume explores numerous methods used in basic science laboratories to characterize cancer-related biomarkers, vital for better managing cancer burden, including cancer risk assessment, cancer diagnosis, determining cancer progression, and therapeutic response. From a radiography method to an examination of single-cell RNA-seq and computational analysis tools in cancer research, this book delves into many techniques that could provide valuable molecular information about the tumor and its microenvironment components. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Biomarkers: Methods and Protocols offers researchers multiple helpful ways to study cancer-associated molecular biomarkers.
During the upgrading of heavy petroleum, asphaltene is the most problematic impurity since it is the main cause of catalyst deactivation and sediments formation. Exploring many aspects related to asphaltenes composition and conversion, Asphaltenes: Chemical Transformation during Hydroprocessing of Heavy Oils highlights the various changes that thes
Contributed articles on historic buildings of Varanasi city, Uttar Pradesh, India; with pictorial representation.
Maharana Pratap has become a subject of respect and pride for the Indians as he has become a symbol pf patriotism, sacrifice and struggle, On remembering his name, the picture of an incomparable warrior with the face aglow with bravery comes into our mind. The war he waged for independence in extremely adverse circumstances will be ever remembered. Despite being the king of mewar, most of his life was spent in forests and mountains, with his supreme willpower and incomparable warfare skills he was able to free mewar at the end. Sacrificing material happiness and gains, his unrelenting struggle for the freedom of his motherland is etched as a golden chapter in die annals of history. Personalities like him are models of inspiration for the whole country and all generations to come. As in today's reckoning when national consciousness seems to be diminishing, Maharana Pratap's character is all the more relevant.
Jordan's diverse socioeconomic make-up encapsulates, like no other Middle Eastern state, both the array of pressing short-term problems facing the region, and the underlying challenges that Arab states will need to face once the current spate of civil conflicts is over: meaningful youth employment, female participation in politics, and integration of refugees into society. This book tells the story of Jordan through the lives of ordinary people, including a political cartoonist, a Syrian refugee, a Jihadist and a female parliamentarian. The raw voices and everyday struggles of these people shine a fresh light on the politics, religion, and society of a culture coming to terms with the harsh ...
Bhagat Singh, 1907-1931, Indian revolutionary and freedom fighter.
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and ...
Automotive Steels: Design, Metallurgy, Processing and Applications explores the design, processing, metallurgy, and applications of automotive steels. While some sheet steels are produced routinely in high volume today, there have been significant advances in the use of steel in the automotive industry. This book presents these metallurgical and application aspects in a way that is not available in the current literature. The editors have assembled an international team of experts who discuss recent developments and future prospects for automotive steels, compiling essential reading for both academic and industrial metallurgists, automotive design engineers, and postgraduate students attending courses on the metallurgy of automotive materials. - Presents recent developments on the design, metallurgy, processing, and applications of automotive steels - Discusses automotive steels that are currently in the early stages of research, such as low-density and high modulus steels that are driving future development - Covers traditional steels, advanced high strength steels, elevated Mn steels and ferrous composite materials
The Volume 2 of the treatise on the Developments in Physiology, Biochemistry and Molecular Biology of Plants provides additional information in the crucial areas for making precise and applied research in the national context, on the one hand, and to unravel the science, on the other hand. In the earlier volume, the theme of publishing this needful treatise has been already made obvious. However, in view of the experiences and enormous advances in plant science research in the last few decades providing enough insight to scan vital research in this century has, almost certainly, enlightened the path to undertake necessary research projects for the benefit of mankind to which we are indispens...