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Cave Microbiomes: A Novel Resource for Drug Discovery
This book details recent findings in the field of cave microbiology and builds on fast-paced efforts to exploit an unconventional and underexplored environment for new microorganisms which may provide an untapped source of drugs: microorganisms from caves.
Actinobacteria in Special and Extreme Habitats: Diversity, Function Roles and Environmental Adaptations
Actinobacteria are highly diverse prokaryotes that are ubiquitous in soil, freshwater and marine ecosystems. Although various studies have focused on the ecology of this phylum, data are still scant on the diversity, abundance and ecology of actinobacteria endemic to special and extreme environments, such as gut, plant, alkaline saline soil, deep sea sediments, hot springs and other habitats. Actinobacteria are well-known producers of a vast array of secondary metabolites, many of which have useful applications in medicine and agriculture. Furthermore, actinobacteria also have diverse functions in different environments apart from antibiotic production. For example, actinobacteria are report...
Actinobacteria in Special and Extreme Habitats: Diversity, Function Roles and Environmental Adaptations, Second Edition
Actinobacteria are well-known producers of a vast array of secondary metabolites. Compared with actinobacteria from temperate habitats, the community structure, diversity, biological activities and mechanisms of environmental adaptation of those actinobacteria in special and extreme environments are relatively unstudied and unclear, and their functions and utilization are even less reported. These actinobacteria are potential new sources of novel natural products and functions for exploitation in medicine, agriculture, and industry. Recent advances in cultivation, DNA sequencing technologies and -omics methods have greatly contributed to the rapid advancement of our understanding of microbia...
Cave Biodiversity
"This book describes the evolution and diversity of the fauna that dwell in caves. Covering both vertebrates and invertebrates, the edited volume brings together ichthyologists, entomologists, ecologists, herpetologists, conservationists, and explorers to provide a nuanced picture of life beneath the earth's surface"--
Microbial Roles in Caves
Caves are dark, underground hollow spaces with relatively constant temperature, high humidity, and limited nutrients. Many caves are associated with karst topography, which is formed by the dissolution of soluble bedrock, such as limestone, dolomite and gypsum, in areas where groundwaters are undersaturated with respect to the minerals in the host rock. Karst landforms spread widely, accounting for approximately 20% of the earth’s dry ice-free surface (Ford and Williams, 2007). As a typical feature of subsurface landscape, karst caves develop globally, with over 50,000 distributed in the United States (Barton and Jurado, 2007). China also has a large contiguous karst terrain, and the Yunna...
Cave Ecology
Cave organisms are the ‘monsters’ of the underground world and studying them invariably raises interesting questions about the ways evolution has equipped them to survive in permanent darkness and low-energy environments. Undertaking ecological studies in caves and other subterranean habitats is not only challenging because they are difficult to access, but also because the domain is so different from what we know from the surface, with no plants at the base of food chains and with a nearly constant microclimate year-round. The research presented here answers key questions such as how a constant environment can produce the enormous biodiversity seen below ground, what adaptations and pec...
Superbugs (WIRED guides)
The number of people dying due to drug-resistant diseases is rising every year. What medical weapons and technologies are being developed to stop this existential threat to all of us? In this brilliantly wide-ranging, one-stop guide WIRED journalist Victoria Turk outlines the reasons for this major crisis in medicine and the steps being taken to control it. She explains the reasons why antibiotics no longer have the miraculous force they once did, and why so many drugs that were once so effective are now falling short. She considers the implications for the future, not just in terms of individual health but humankind's ability to counter pandemics. She looks at the latest research into new antibiotics, preventative medicine, diagnostic techniques and resistance-resistant treatments. And she addresses the fundamental question: are new medical breakthroughs sufficient to safeguard our health in the future?
Between Making And Knowing: Tools In The History Of Materials Research
This book is indexed in Chemical Abstracts ServiceThis book offers a comprehensive sketch of the tools used in material research and the rich and diverse stories of how those tools came to be. We aim to give readers a sense of what tools materials researchers required in the late 20th century, and how those tools were developed and became accessible. The book is in a sense a collective biography of the components of what the philosopher of science, Ian Hacking, calls the 'instrumentarium' of materials research. Readers should gain an appreciation of the work materials researchers put into developing and using such tools, and of the tremendous variety of such tools. They should also gain some insight into the material (and hence financial) prerequisites for materials research. Materials research requires funding for the availability and maintenance of its tools; and the category of tools encompasses a broad range of substances, apparatus, institutions, and infrastructure.
Can J Microbiol
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