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Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alteration...
O curso de Pós-Graduação lato sensu de Especialização em Análise Ambiental do IFCE campus Camocim foi criado para oportunizar o incremento de massa crítica às intenções de desenvolvimento local e regional, visando excelência em P,D&I e com ideias fixas na sustentabilidade ambiental. Tais expressões se materializam nos 25 Trabalhos de Conclusão de Curso (TCC) organizados neste livro em artigos por ordem alfabética dos respectivos títulos.
This timely book examines the significant challenges and possible solutions for enabling efficient modernization of electric power systems. It addresses rapidly changing electricity infrastructure needs and technical requirements and provides a practical introduction to the past, present, and future of energy efficiency and power quality concepts. The book also looks at recent developments in custom power conditioners that help improve the performance of transmission and distribution systems, ensure reliability, and reduce costs. Modernization of Electric Power Systems is a valuable resource for practicing engineers, students, and researchers interested in exploring and implementing energy efficiency and power quality in modern energy systems with renewables.
Mounting evidence in the last years has demonstrated that self-regulation of brain activity can successfully be achieved by neurofeedback (NF). These methodologies have constituted themselves as new tools for cognitive neuroscience establishing causal links between voluntary brain activations and cognition and behavior, and as potential novel approaches for clinical applications in severe neuropsychiatric disorders (e.g. schizophrenia, depression, Parkinson´s disease, etc.). Current developments of brain imaging-based neurofeedback include the study of the behavioral modifications and neural reorganization produced by learned regulation of the activity of circumscribed brain regions and neu...
Company leaders feel the urgency to transform their organizations in the face of digital disruption. New rivals are digitizing whatever can be digitized to attack incumbents' value chains, gaining market share, eroding margins, and wreaking havoc to the competitive landscape in virtually every industry. For large and midsized companies, the imperative to transform is clear. How to transform is another matter. The hard truth is that despite leaders' best efforts, and billions spent in pursuit of digital transformation, the vast majority of organizational change programs fizzle, falling well short of their expected impacts. Because failed transformation programs put incumbents behind the eight...
True bugs (Heteroptera) are a diverse and complex group of plant-feeding and predatory insects important to food production, human health, the global economy and the environment. Within the nearly 43,000 species described around the world, Neotropical true bugs are particularly diverse, and much remains to be discovered about their biology and relations with other species. Inspired by the need for a comprehensive assessment, True Bugs (Heteroptera) of the Neotropics is the most complete and thorough review ever published. Experts in each of the seven infraorders have drawn together the scattered literature to provide detailed treatments of each major taxon. The most common and important spec...
Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regarding the epidemiology of insulin resistance in the pediatric population. The second section of the book explores pathophysiology, including current knowledge of the molecular, metabolic, and physiologi...
Cardiac Resynchronization Therapy continues to evolve at a rapidpace. Growing clinical experience and additional clinical trialsare resulting in changes in how patients are selected for CRT. This new edition of the successful Cardiac ResynchronizationTherapy builds on the strengths of the first edition, providingbasic knowledge as well as an up-to-date summary of new advances inCRT for heart failure. Fully updated to include information ontechnological advances, trouble shooting and recent key clinicaltrials, and with nine new chapters, this expanded text provides thelatest information, keeping the reader up-to-date with this rapidlyevolving field. The second edition of Cardiac Resynchronization Therapyis an essential addition to your collection.
Digital disruption: seemingly out of nowhere, startups and other tech-savvy disruptors attack. In Digital Vortex, you will learn how to use the business models and strategies of startups to your own advantage. Most importantly, you will learn how to build the agility to anticipate threats, sense opportunities, and seize them before your rivals do.
The four-volume set LNCS 7333-7336 constitutes the refereed proceedings of the 12th International Conference on Computational Science and Its Applications, ICCSA 2012, held in Salvador de Bahia, Brazil, in June 2012. The four volumes contain papers presented in the following workshops: 7333 - advances in high performance algorithms and applications (AHPAA); bioinspired computing and applications (BIOCA); computational geometry and applicatons (CGA); chemistry and materials sciences and technologies (CMST); cities, technologies and planning (CTP); 7334 - econometrics and multidimensional evaluation in the urban environment (EMEUE); geographical analysis, urban modeling, spatial statistics (Ge...