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Alcohol-Associated Liver Disease - From Pathogenesis to Treatment
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism
The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.
Alcohol and Alcohol-related Diseases
Alcohol is one of the major risk factors for negative health outcomes worldwide. It accounts for more than 60 alcohol-related diseases, ranging from addiction, through liver cirrhosis, to cancer. Collectively, these conditions account for mortality and morbidity that make alcohol use one of the leading preventable causes of disability adjusted life-years (DALYs) lost globally. In this book, an international faculty covers all aspects of alcohol-related disorders, ranging from addiction/alcohol use disorders (AUD) to alcohol-related diseases of other organs such as liver, heart or cancer. A special focus is to reach out to primary care physicians who are in the front line of this major health...
Advances in Liver Inflammation and Fibrosis due to Infectious Diseases
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Metabolismo del sistema digestivo, del hígado, de la vesícula y de las vías biliares
La formación del médico general requiere el conocimiento científico del comportamiento del metabolismo de los tejidos y sistemas en condiciones de salud para poder establecer un diagnóstico acertado y las orientaciones adecuadas al surgir fallas de los mismos en el curso de las enfermedades. Por lo tanto, un propósito central de este libro es aportar conocimiento actualizado acerca de las características del metabolismo del sistema digestivo, el hígado y las vías biliares, así como de los mecanismos de adaptación entre estos y los demás tejidos en condiciones fisiológicas que explican la respuesta integrada a las diferentes demandas y mecanismos de señalización en condiciones d...
Homocysteine in Health and Disease
This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.
