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Neurobehavioral Toxicity
In establishing how certain chemicals can cause behavioural disorders, the process of neurotoxicity risk assessment poses significant challenges to every discipline within neuroscience. In this volume, leaders from industrial, academic, and government settings share insights on behavioural measurement in neurotoxicity risk assessment, and address the critical scientific issues arising from the expanding role of neurobehavioral toxicology in public policy development.; The authors set out to provide a comprehensive and authoritative review of current methods in the analysis and interpretation of neurobehavioural toxicology. Coverage begins with a discussion of criteria for determining neurotoxic potential. The next section examines neurobehavioural evaluations in developmental neurotoxicity. Subsequent sections focus on activity and observational data and applications of schedule-controlled operant behaviour in toxicity testing. The contributors address controversies surrounding the suitability and interpretation of procedures designed for neurotoxicological assessments. Some case studies are also included.
The Effects of Aging and Environment on Vision
This book derives from a symposium conducted in San Francisco CA, entitled "Environmental Design for Optimum Vision in the Elderly" that was sponsored by the American Aging Association, October 11-12, 1985. Presentations from this symposium comprise the core content of this volume. However, manuscripts have also been accepted from additional authors whose topics and research findings increase the scope and goals of this volume. Previously unpublished data is found in several of the chapters. In addition new data and references have been incorporated at the end of chapters in order to provide a current update of the subject. The broad aims of the papers in this volume were to examine the effe...
Combination Therapy in Urological Malignancy
Any discussion of the present success in management of urological cancers evokes a mixed response. Oncologists and urologists can enjoy the success with chemotherapy for testicular cancers but cannot forget the dismal results with any form of treatment, other than surgery, for renal carcinoma. But these are the less frequent urolegi cal tumours: what are the attitudes to the more common prostate and bladder cancers. Intensive study, many clinical trials and much debate lead us to the conclusion that we understand them better, we can tailor the treatment more appropriately to the individual patient but there remains some uncertainty as to the overall success that we have achieved. There have ...
The Medical Management of Prostate Cancer II
How to treat advanced prostatic cancer remains controversial, despite intense basic and clinical research investigating the pathogenesis and natural history of this unique cancer highly prevalent in elderly males. Nine experts were asked to meet and discuss the facts. This resulting monograph gives an overview of the available knowledge on all aspects of the subject. The objective evaluation and consensus opinion of the authors presented here set this book apart from other publications with conflicting viewpoints. For readers eager to obtain a comprehensive and balanced view of the thousands of clinical contributions and clear advice on the choices, this book is a must.
Plant Chromosomes
Finally - a guide to cytological techniques written specifically for the plant chromosome researcher and student. Plant Chromosomes: Laboratory Methods thoroughly covers all important approaches to the study of plant chromosomes. It reviews each specific approach and describes requisite experimental techniques. These practical descriptions cover basic, standard techniques as well as the most recent research advances and state-of-the-art technologies. Plant Chromosomes: Laboratory Methods allows you to build on the knowledge of its expert authors, who have first-hand experience with the ins and outs of each approach. Through hundreds of trouble-shooting suggestions it also helps you avoid experimental pitfalls by providing invaluable tips at critical points in the experimental process. This book gives you the information you need to improve the power of your plant chromosome research - saving you time and effort in the process. No other single volume contains so much practical information on this topic.
Clinical and Molecular Aspects of Neurotropic Virus Infection
In the summer of 1984, both of us were working with Professor Yechiel Becker in the Laboratory for Molecular Virology at the Hebrew University-Hadassah Medical center in Jerusalem. During a discussion about the increasing number of specialized journals and monographs, Dr. Becker pointed out that none covered both the clinical and molecular aspects of neurotropic virus infections, and he urged us to develop such a book with the help of colleagues who were conducting highly-regarded research in their individual areas related to neurotropic viruses. The responses to our request were gratifying, and each contribution provided both a comprehensive clinical description of the neurologic disease pr...
Virus Infections of Ruminants
Hardbound. As its title suggests, this book is intended to give exhaustive information on virus infections and diseases occurring in ruminants. Each virus and corresponding disease is described in a separate chapter, and the chapters are ordered according to current virus classification. Contributing authors are experts on the virus and disease they describe. Where necessary, the text is accompanied by tables and pictures. The accent is placed on diagnosis of the disease by clinical observations including epizootological data. There is also a description of the laboratory procedures of diagnostic virology, and suggestions concerning control measures (e.g. vaccination and/or eradication policy).This book should prove indispensable to: the practising veterinarian, by facilitating recognition of a viral disease, and giving advice on collecting appropriate specimens for laboratory investigation; the veterinary virologist by aiding the choice of appropriate
Metal Ions in Biological Systems
This book describes drug metal-ion interactions in the gut and deals with the deficiency of zinc and iron and their pharmacological use. It covers anti-inflammatory activities of copper and gold complexes and considers the role of metal ions and chelating agents in anti-viral chemotherapy.
Viral Messenger RNA
The nucleotide sequence of the gene from which messenger RNA mole cules are transcribed is in a form that can be translated by cellular ribosomes into the amino acid sequence of a particular polypeptide, the product of the gene. The discovery of messenger RNA more than twenty years ago led to a series of studies on its organization and function in cells in the presence of infecting viruses. This volume is devoted to current studies in the field of cellular and viral messenger RNA. The studies presented provide an insight into molecular and genetic aspects of messenger RNA. Special attention was paid by the authors to the molecular organization of mRNA species, to the processing of mRNA molec...
