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Radiation in Tissue Banking
This important book discusses the need for gamma irradiation in the processing of tissue allografts. With particular emphasis on tissue banking in the Asia-Pacific region, it covers a wide range of issues in tissue banking, including the basic science of radiation, quality control of the irradiation process, and clinical applications of irradiated bone grafts and amnions. A compulsory textbook for the well-regarded Singapore-based IAEA/NUS Diploma Course in Tissue Banking, it is also a useful guide for tissue bankers in establishing quality systems in their banks. Whether they be tissue banking students, tissue graft producers, radiation scientists, or transplantation surgeons, readers of this book will discover the latest developments in this exciting interdisciplinary field.
Human Amniotic Membrane: Basic Science And Clinical Application
This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.The amnion comes close to being the ideal biological membrane or dressing — readily available, inexpensive to procure and process. Its basic science is discussed in detail — anatomy, biological and biomechanical properties.It can be procured from the placenta in normal vaginal deliveries and from Caesarean Sections. Processing is by freeze-drying or by air-drying process with sterilisation using gamma irradiation.The product has low antigenicity, has anti-microbial properties with ability to enhance epithelisation with marked relief of pain. It is useful as a dressing for wounds — flap wounds, burn wounds, injury wounds, diabetic ulcers, leprous ulcers and post-surgery wounds and post-radiation wounds. It is also used as a biological scaffold for cells in tissue engineering. Its ophthalmic applications include treatment of corneal ulcers and conjunctival tumours. Oral uses include gingiva depigmentation and periodontal regeneration.
Allograft Procurement, Processing And Transplantation: A Comprehensive Guide For Tissue Banks
This book is written as a comprehensive guide for all tissue bank operators to procure and process bone and soft tissue allografts of highest quality standards for safe tissue transplantation practice in patients who require musculoskeletal tissue allograft transplantation. This comprehensive guide includes donor selection criteria, aseptic procurement techniques, laboratory testing and processing of grafts by deep freezing or freeze drying. It also includes sterilization of tissue grafts using gamma irradiation. Quality controls of tissue grafts are discussed in depth. The clinical transplantation of bone and soft tissue allografts is also discussed, with special consideration given to pote...
Advances in Tissue Banking
This is the most comprehensive volume dealing with tissue banking presently available, with 27 contributions from the most distinguished and experienced practitioners in the field: surgeons, microbiologists and tissue bankers. Safety of allografts is now a major concern due to possible microbial and viral contamination of tissues, even in the most sophisticated centres. Thus, publication here of the International Atomic Energy Agency's Code of Practice for the Radiation Sterilisation of Tissues is important, as is their guidance on Standards and Public Awareness regarding this often misunderstood technology. The volume spans all the methodologies used in the field and covers a spectrum of ti...
Advances In Tissue Banking, Vol. 7
This is the most comprehensive volume dealing with tissue banking presently available, with 27 contributions from the most distinguished and experienced practitioners in the field: surgeons, microbiologists and tissue bankers.Safety of allografts is now a major concern due to possible microbial and viral contamination of tissues, even in the most sophisticated centres. Thus, publication here of the International Atomic Energy Agency's Code of Practice for the Radiation Sterilisation of Tissues is important, as is their guidance on Standards and Public Awareness regarding this often misunderstood technology.The volume spans all the methodologies used in the field and covers a spectrum of tiss...
Sterilisation of Tissues Using Ionising Radiations
Existing methods and processing for sterilising tissues are proving inadequate in many instances. Infections have been transmitted from the graft to the recipient and in the USA the Centre for Disease Control and other regulatory bodies have drawn attention to the need for a reliable end sterilisation method which does not damage the functionality of the final tissue. Safety of surgical allografts is, therefore, a major concern due to microbial and viral contamination of tissues which is now a problem even in the most sophisticated centres.The Presidents of the main Professional Association of Tissue Banks; American, European and Latin American met in Vienna to review the situation and concl...
Advances in Tissue Banking
This important book provides the only published information in the inter-disciplinary field of tissue banking. It gives comprehensive coverage of the regulatory framework of the subject, as well as production and sterilisation of tissue allografts, (bone, skin and new substitutes). The use of tissue allografts in orthopaedic and replacement surgery for the treatment of burns. etc. is described.
Advances In Tissue Banking, Vol 3
This important book provides new information about the inter-disciplinary field of tissue banking and related clinical applications, and complements the previous two volumes. It gives comprehensive coverage of the regulatory framework of the subject, as well as production and sterilisation of tissue allografts (bone, skin and new substitutes). The use of tissue allografts in orthopaedic and replacement surgery for the treatment of burns, etc. is described.
Legal Basis Of Global Tissue Banking: A Proactive Clinical Perspective
The banking of human tissues for clinical transplantation has grown exponentially in the past 10-15 years. Tissue banks have been set up throughout the world, initially on an ad hoc basis. More recently these have grown and in many countries have linked up with larger international companies. While standards for the procurement, processing and storage of the tissues have kept pace with the growth of the subject, this is not so with the legal considerations associated with the practice. There is no unified legal system which is internationally operated. Europe, USA, Asia, Latin America, China have been developing legal systems on an individual basis.This book describes the present state of the development of laws to control and make the banking and use of tissues legal and safe. It describes, for the first time, the current systems which are used throughout the world and points the way to setting up a harmonized global legal system.
Bone Grafts And Bone Substitutes: Basic Science And Clinical Applications
This book provides the latest updates on the major challenges of bridging large bone defects, where options range from autografts, “tissue engineered bone”, biomaterials (hydroxyapatite, polycaprolactone and third generation biomaterials) to prostheses. Emphasis has been made on bone tissue engineering, the current state-of-the-art in this field, problems encountered with cell culture technology, scaffolds and bone growth factors (including genomics) and the use of gene therapy for the application of bone growth factors. Attention has also been given to the use of bone autografts. It also covers the use of biomaterials and prostheses as other options for reconstruction. Clinical applications, in addition to the basic science, are also included throughout the discussions.
