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Focus on Autism Research
This new book brings together the latest research in the battle against autism. According to numerous news reports, the increase in special needs children has reached epidemic proportions in the United States. Autism is a complex developmental disability that typically appears during the first three years of life. The result of a neurological disorder that affects the functioning of the brain, autism and its associated behaviours have been estimated to occur in as many as 2 to 6 in 1,000 individuals. Autism is four times more prevalent in boys than girls and knows no racial, ethnic, or social boundaries. Autism is a spectrum disorder. The symptoms and characteristics of autism can present themselves in a wide variety of combinations, from mild to severe. Although autism is defined by a certain set of behaviours, children and adults can exhibit any combination of the behaviours in any degree of severity. People with autism process and respond to information in unique ways. In some cases, aggressive and/or self-injurious behaviour may be present.
Behavioral Neuroscience
What do we mean by "behavioral neuroscience?" This volume aims at providing an overview of behavioral neuroscience and deepening neuronal mechanisms and brain circuits that regulate the fundamental aspects of human behavior, such as cognitive and emotional functions. It is intended to give the reader the most up-to-date vision of how the interaction between biological mechanisms and neurocognitive processes leads to complex and highly organized behaviors.In recent years the strong impulse given to research on behavioral neuroscience has produced a large literature that documents the high level of complexity of the issue, for which it is necessary to provide a reasoned multidimensional analysis able to integrate the expertise of different disciplines.The book offers an excellent synopsis of perspectives, methods, empirical evidences, and international references. Therefore, it represents an extraordinary opportunity to target neuroscientific hot topics and to outline new horizons in the study of the relationship between brain and behavior.
The Autisms
The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the human disease. These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated into novel, rational therapies. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments.
Ethical Sense and Literary Significance
This study blends together ethical philosophy, neurocognitive-evolutionary studies, and literary theory to explore how imaginative discourse addresses a distinctively human deep sociality, and by doing so helps shape cultural and literary history. Deep sociality, arising from an improbable evolutionary history, both entwines and leaves non-reconciled what is felt to be significant for us and what ethical sense seems to call us to acknowledge as significant, independent of ourselves. Ethical Sense and Literary Significance connects literary and cultural history without reducing the literary to a mere expression of something else. It argues that affective differences between non-egocentric and...
Breaking the Cycle of Opioid Addiction
An evidence-based guide to using cannabis to enhance pain relief safely, effectively, and economically while reducing the risks of opioid addiction Opioid addiction has exploded to epidemic proportions in the U.S. Drug overdose is now the leading cause of accidental death. In 2012, 259 million prescriptions were written for opioids—more than enough to give every American adult their own bottle of pills. Uwe Blesching, author of The Cannabis Health Index, clearly and thoroughly lays out the overwhelming benefits of using cannabis—not only to reduce the nation’s dependence on opioids—but also to manage the craving and withdrawal symptoms of opioid addiction, and especially to address t...
Trust, Knowledge and Society
What do loving relationships, shared knowledge, innovative companies and legitimate governments have in common? They all flourish with trust and wither without. Against the astonishing scope of trust's influence in our societies we find statistics showing that trust has been dramatically declining in recent decades – a trend readily confirmed by real life events. This is the troubling starting point the book seeks to address. Through exploring the topic of trust the book provides novel perspectives on how to heal the internal divisions in the west, and more profoundly, shows how it is trust that defines successful societies in general.
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an exten...
