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Contains essential facts and concepts spanning many of the important drug classes. Features an authoritative section on general methodology and regulatory issues. The molecular biology and pharmacology of key receptor types are considered along with the detailed pharmacodynamics of a wide range of therapeutic drug groups.
Small pelagic fish species found in lakes and introduced to reservoirs dominate by volume and contribute some of the most important inland fisheries in Africa with steadily increasing catches and additional potential. This circular reviews the status and importance of the pelagic fish and fisheries, together with small fish in general, for sustainable and healthy livelihoods in Africa. It reviews the biology and biological production of the most important pelagic species in lakes and reservoirs as well as the impacts of environmental and climatic variation on the stocks of these species. It examines and discuss the various capture techniques together with potential of improvements in the fisheries and associated processing and national and regional trade within Africa. The knowledge generated by the circular will be useful for policy makers and development practitioners to design and implement more effective policies, strategies and programs that will contribute to reducing the food insecurity and conflicts that currently affect the people in sub-Saharan Africa.
Twenty US and European contributors from academia and pharmaceutical companies present a tripartite discussion of the short but impressive history of drug treatment of essential hypertension, focusing on: medicinal chemistry, pharmacology, and the clinical picture. Each successive generation of drugs (e.g. beta-blockers, calcium antagonists, and ACE-inhibitors) permits more precise tailoring to individual patient needs, as well as further elucidating the pathophysiology of the disease. Those interested in integrative medicine will appreciate the paper on treating hypertension in the elderly and diabetics, which refers to non-drug lifestyle approaches to lowering blood pressure. Annotation copyrighted by Book News, Inc., Portland, OR
When the English conquered New Netherland in 1664, they found a well-established society that was firmly held together by a Dutch-modelled government and church, and which maintained continuous communication with its fatherland, the Dutch Republic. Combined sources from American and Dutch archives provide a lively picture of every-day life in this colony. Newly wealthy traders, craftsmen and other workers, and people who survived thanks to a well-organized system of poor relief are the main characters in this study of one of its major communities, Beverwijck on the upper Hudson (present-day Albany, New York). Beavers and shell beads that served as money, daily visits by Indians, and the presence of African slaves make clear that Beverwijck was not only Dutch, but a new, 'American' society, as well.
Advances in Pharmacological Research and Practice, Volume 2: Receptors and Centrally Acting Drugs presents the proceeding of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the developments in the fields of receptors and centrally acting drugs as well as in pharmacokinetics and drug metabolism. Organized into two sections encompassing 25 chapters, this volume begins with an overview of prejunctional regulation of neuromuscular transmission. This text then explores the whole-body autoradiography that is used extensively in toxicological research and screening. Other chapters consider the three major classes of models used in pharmacokinetics. This book discusses as well the various aspects of melanin–drug interactions. The final chapter deals with the investigation on the melanin affinity of amphetamine derivatives. This book is a valuable resource for pharmacologists, pharmacokineticists, and researchers.
The hemodynamic mechanisms of hypertension are often limited to the study of three dominant parameters: blood pressure, cardiac output and vascular resis tance. Accordingly, the development of hypertension is usually analyzed in terms of a 'struggle' between cardiac output and vascular resistance, resulting in the classical pattern of normal cardiac output and increased vascular resistance, thus indicating a reduction in the caliber of small arteries. However, during the past years, the clinical management of hypertension has largely modified these simple views. While an adequate control of blood pressure may be obtained with antihypertensive drugs, arterial complications may occur, involvin...
The previous volume on Antihypertensive Agents in the Handbook of Experi mental Pharmacology, published in 1977, was edited by the late Franz Gross from the Department of Pharmacology in Heidelberg, who was one of the grand old men in hypertension research. Now, more than 10 years later, it is necessary to update this volume. From the early days of antihypertensive drug treatment, starting about 30 years ago with drugs such as reserpine and guanethidine, the pharmacology of cardiovas" cular therapy has evolved into a highly sophisticated and effective therapeutic regimen. The major breakthroughs in the 1960s were the introduction of diuretics and beta-blockers. Then, in the 1980s, came the c...
This third edition of the Principles of Banking Law provides an authoritative treatment of both domestic and international banking law. This edition contains expanded coverage of developments in other comparable jurisdictions, internet banking services and money laundering.