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This book presents the selected proceedings of 2nd International Conference on Recent Advances in Manufacturing (RAM 2021). The book provides insights to current research trends and opportunities in modelling and optimization of manufacturing processes and systems. The topics covered include modelling analysis, computing and simulation, traditional and non-traditional optimization techniques, surface coating methods, additive manufacturing processes, CAD/CAM, robotics and automation, welding and joining processes, supply chain management and CAE and reverse engineering. This book will be a good reference for beginners, researchers and professionals interested in modelling and optimization related to manufacturing engineering and related fields.
Research on the biochemistry and molecular biology of lipids and lipoproteins has experienced remarkable growth in the past 20 years, particularly with the realization that many different classes of lipids play fundamental roles in diseases such as heart disease, obesity, diabetes, cancer and neurodegenerative disorders. The 5th edition of this book has been written with two major objectives. The first objective is to provide students and teachers with an advanced up-to-date textbook covering the major areas of current interest in the lipid field. The chapters are written for students and researchers familiar with the general concepts of lipid metabolism but who wish to expand their knowledg...
For all Muslims the QurE3/4an is the word of God. In the first centuries of Islam, however, many individuals and groups, and some ShiEis, believed that the generally accepted text of the QurE3/4an is corrupt. The ShiEis asserted that redactors had altered or deleted among other things all passages that supported the rights of EAli and his successors or that condemned his enemies. One of the fullest lists of these alleged changes and of other variant readings is to be found in the work of al-SayyArA (3rd/9th century), which is indeed among the earliest ShiEi books to have survived. In many cases the alternative readings that al-SayyArA presents substantially contribute to our understanding of early ShiEi doctrine and of the early and numerous debates about the QurE3/4an in general.
The Human body is a vast network of interacting genes, proteins, and metabolites. These components, which may be considered host factors, change under disease, treatment or healthy condition. While treatment of many diseases depends on therapeutic drugs, vaccines remain the most effective long-term public health intervention to prevent infectious diseases. To date, vaccines have been developed to treat entire populations with little provision for predisposing individual host factor differences. However, the use and application of vaccines is facing multiple challenges with increasing numbers of vaccine non-responders and vaccine-relapsed individuals. The cause of this complication is partially due to host-factors. Another challenge is the adverse effects of vaccines in patients with primary immunodeficiency or autoimmune diseases, as well as vaccine-waning immunity in ageing populations, obese populations, or those with co-infection. To overcome these challenges, the solution may be the design, and formulation of precision vaccines, which are patient-specific.
Friction-stir welding (FSW) is a solid-state joining process primarily used on aluminum, and is also widely used for joining dissimilar metals such as aluminum, magnesium, copper and ferrous alloys. Recently, a friction-stir processing (FSP) technique based on FSW has been used for microstructural modifications, the homogenized and refined microstructure along with the reduced porosity resulting in improved mechanical properties. Advances in friction-stir welding and processing deals with the processes involved in different metals and polymers, including their microstructural and mechanical properties, wear and corrosion behavior, heat flow, and simulation. The book is structured into ten ch...
Good posture and strong core muscles are essential for most athletic movements, but also for everyday activities. Among them, walking and running require lumbo-pelvic stability and mobility for efficient movement and high-level performace. This is especially important during a large range of trunk motions when changing the direction of movement, an abrupt walk to run transition, or extreme uphill and downhill walking or running. Such repetitive trunk loading over time can contribute to occurence of back problems and lower limb injuries. To avoid these unwanted effects, a novel approach to studying the physiology of locomotion in relation to spine motion and balance function is required. This...
This book presents an in-depth analysis covering climatic and weather conditions, house and building development history, construction methods and technologies, and environmental conditions. It provides relevant house and building information and highlights recent advances in hot and humid regions, as well as developments in other regions that are relevant to hot and humid climates. The countries in hot and humid regions, which include the tropical countries, the Middle Eastern countries around the Mediterranean, and many countries of Central Asia and Africa, are home to some of the most challenging conditions in the world in terms of house and building design and construction, and in terms ...
This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice. To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute...