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Geriatrics
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White Gold
During the past fifty years, Canadians have seen many of their white-water rivers dammed or diverted to generate electricity primarily for industry and export. The rush to build dams increased utility debts, produced adverse consequences for the environment and local communities, and ultimately resulted in the layoff of 25,000 employees. White Gold looks at what went wrong with hydro development, with the predicted industrial transformation, with the timing and magnitude of projects, and with national and regional initiatives to link these major projects to a trans-Canada power grid.
Medical Directory
A listing of medical practitioners registered with the General Medical Council. Includes England, Scotland, Wales, and Northern Ireland. Data includes name, address, degrees, colleges, appointment, memberships, and publications. Also contains information on United Kingdom hospitals, NHS trusts, and boards of health.
Mechanisms in Parkinson's Disease
Parkinson's disease (PD) results primarily from the death of dopaminergic neurons in the substantia nigra. Current PD medications treat symptoms; none halt or retard dopaminergic neuron degeneration. The main obstacle to developing neuroprotective therapies is a limited understanding of the key molecular mechanisms that provoke neurodegeneration. The discovery of PD genes has led to the hypothesis that misfolding of proteins and dysfunction of the ubiquitin-proteasome pathway are pivotal to PD pathogenesis. Previously implicated culprits in PD neurodegeneration, mitochondrial dysfunction, and oxidative stress may also act in part by causing the accumulation of misfolded proteins, in addition to producing other deleterious events in dopaminergic neurons. Neurotoxin-based models have been important in elucidating the molecular cascade of cell death in dopaminergic neurons. PD models based on the manipulation of PD genes should prove valuable in elucidating important aspects of the disease, such as selective vulnerability of substantia nigra dopaminergic neurons to the degenerative process.
Meyler's Side Effects of Psychiatric Drugs
"The unwanted effects of medications used in psychiatry can adversely affect a treatment plan. This volume will be critical in helping psychiatrists and mental health professionals assess the adverse effects of drugs such as antidepressants, mood stabilizers, hypnosedatives, and antipsychotic drugs." "This book summarizes the adverse effects of a large range of Psychiatric drugs. The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler's Side Effects of Drugs: The Encyclopedia of Adverse Drug Reactions and Interactions, and the latest volumes in the companion series, Side Effects of Drugs Annuals."--BOOK JACKET.
European Handbook of Neurological Management
The European Handbook of Neurological Management, published in collaboration with the European Federation of Neurological Societies (EFNS), is a unique book that brings together peer-reviewed guidelines for the treatment and management of neurological disease. For the first time, neurologists can find advice on management aspects of most neurological disorders that is either evidence-based or, where the evidence is inadequate, the consensus guidance of an international European panel of experts. The guidelines fall naturally into sections that cover: Investigation: cerebrospinal fluid analysis, imaging, diagnostic antibodies and skin biopsy Major neurological diseases: stroke, migraine, Park...
