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The Globe Artichoke Genome
This book presents the latest information on the genetics and genomics of the globe artichoke. It focuses on the latest findings, tools and strategies employed in genome sequencing, physical map development and QTL analyses, as well as genomic resources. The re-sequencing of four globe artichoke genotypes, representative of the core varietal types in cultivation, as well as the genotype of cultivated cardoon, has recently been completed. Here, the five genomes are reconstructed at the chromosome scale and annotated. Moreover, functional SNP analyses highlight numerous genetic variants, which represent key tools for dissecting the path from sequence variation to phenotype, as well as for designing effective diagnostic markers. The wealth of information provided here offers a valuable asset for scientists, plant breeders and students alike.
Ovarian Cancer Biomarkers
This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.
Personalization in Gynecologic Oncology
This book thoroughly illustrates the designed and tailored medical approaches for tumors of the female reproductive organ. The chapters explore different cancer species such as ovarian cancer, endometrial cancer, cervical cancer, etc. Various treatment modalities such as immunotherapy and histotype-specific treatment are delivered, and it offers a chapter on how genome-wide analysis contributes to personalized treatment. It is essential to understand this concept because many molecular target drugs and the prevalence of genome-based analysis in clinical settings have enabled us to introduce valid precision medicine in the field of gynecologic oncology. Chapters explain the stream of transition from conventional standardized treatment to personalized treatment and address future perspectives. Personalization Gynecologic Oncology is a well-designed source for beginning to advanced oncologists, gynecologists, geneticists, genetic counselors, and nurses. Offering the latest treatment strategies, the Editor hopes the ideas presented here will be a foundation for further development in the field.
Latinas in the United States, set
Latinas in the United States: A Historical Encyclopedia records the contribution of women of Latin American birth or heritage to the economic and cultural development of the United States. The encyclopedia, edited by Vicki L. Ruiz and Virginia Sánchez-Korrol, is the first comprehensive gathering of scholarship on Latinas. This encyclopedia will serve as an essential reference for decades to come. In more than 580 entries, the historical and cultural narratives of Latinas come to life. From mestizo settlement, pioneer life, and diasporic communities, the encyclopedia details the contributions of women as settlers, comadres, and landowners, as organizers and nuns. More than 200 scholars explo...
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Cuban Medicine
Health services have long been characterized by inequities and contradictions urban concentration of health resources versus a dearth of rural services and, within the urban situation, relatively efficient services f a few large institutions versus the conglomeration of small, inefficient, and largely autonomous units. Using the Cuban system as a model, Danielson discusses the ingrredients involved in the transformation into an equitable medical sysÂtem. The sociopolitical formation of new health workers, the continuous emphasis on rural and primary services, the involvement of all groups, including specialists, in the general fanning process, and a pragmatic style of politically inspired...
