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Historical studies on the involvement of architecture in twentieth-century politics have overlooked its contribution to building Spain’s democracy. This pioneering book seeks to fill that void. Between the late 1970s and early 1990s, Spain founded representative institutions, launched its welfare state, and devolved autonomy to its regions. The study brings forth the architectural incarnation of that threefold program as it deployed in the Valencian Country, a Catalan-speaking region on Spain’s Mediterranean shores. There, social democratic authorities mobilized architects, planners, and graphic artists to devise a newly open public sphere and to recover a local identity that Franco’s ...
In the World Library of Psychologists series, international experts present career-long collections of what they judge to be their most interesting publications – extracts from books, key articles, research findings, and practical and theoretical contributions. Marc H. Bornstein has published widely in experimental, methodological, comparative, developmental, and cultural science as well as neuroscience, pediatrics, and aesthetics. In this volume, he has collected an integrated series of his papers on parenting. Many disciplines over many centuries have expounded on parenting, but theory and opinion have prevailed. Bornstein initiated efforts to make parenting an evidence-based field of st...
This book, written by respected experts, discusses in detail the latest developments in targeted oncology therapy using small molecules. It covers a wide range of small molecules, including tyrosine kinase inhibitors, mTOR, MEK, PARP, and multikinase inhibitors, as well as cell cycle and NTRK interacting agents. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the advances being made will mean significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book is the third edition of Small Molecules in Oncology, but has now been divided into two volumes, with the other volume focusing specifically on small molecules in hematology.
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Long before the mid-nineteenth century, thousands of people were frequently moving between North America - specifically, the United States and British North America - and Leghorn, Genoa, Naples, Rome, Sicily, Piedmont, Lombardy, Venice, and Trieste. Predominantly traders, sailors, transient workers, Catholic priests, and seminarians, this group relied on the exchange of goods across the Atlantic to solidify transatlantic relations; during this period, stories about the New World passed between travellers through word of mouth and letter writing. Blurred Nationalities across the North Atlantic challenges the idea that national origin - for instance, Italianness - constitutes the only significant feature of a group's identity, revealing instead the multifaceted personalities of the people involved in these exchanges.
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