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Proceedings of the 1997 International Workshop on Biophysics of Electron Transfer: Fundamental Aspects and Applications, held in Bressanone, Italy, October 8-10, 1997
About two centuries after the communication by Sir Percival Pott that the "chimney sweeper disease" was a cancer and its suggestion that active compounds of soot were the causative agents, and about one century after the description of urinary bladder cancer in dye workers, an enormous number of substances have been synthesized and have probably come into contact with man. Research in cancer prevention is of primary importance, and may receive continuous support from new discoveries on cancer etiology and pathogenesis. If one accepts the multistage model of chemical carcinogenesis, one has also to accept that many events occur between the contact of carcino genic compounds and their specific targets and the development of a clinically recognizable neoplasm. Thus, animal studies become essential to elucidate the different steps by which chemical carcinogens induce neoplasia. The analysis of these steps and the comparative evaluation of experimental models is essential to an understanding of pathogenesis.
In the 19th century, pure mathematics research reached a climax in Germany, and Carl Friedrich Gauss (1777–1855) was an epochal example. August Ferdinand Möbius (1790–1868) was his doctoral student whose work was profoundly influenced by him. In the 18th century, it had been mostly the French school of applied mathematics that enabled the rapid developments of science and technology in Europe. How could this shift happen? It can be argued that the major reasons were the devastating consequences of the Napoleonic Wars in Central Europe, leading to the total defeat of Prussia in 1806. Immediately following, far-reaching reforms of the entire state system were carried out in Prussia and ot...
The topics contained in this book represent timely and currently exciting areas of research focused on mitochondria. It forms a comprehensive and up-to-date record of present knowledge at the molecular level of many important mitochondrial processes. Major achievements as well as new openings in the field have been stressed in many of the contributions to the book. Thus, it represents a valuable source and reference book, comprising the most recent results in this area. The topics treated should attract the attention of scientists from various fields, who are interested in bioenergetics, molecular biology and pathology of mitochondria.
The informational nature of biological organization, at levels from the genetic and epigenetic to the cognitive and linguistic. Information shapes biological organization in fundamental ways and at every organizational level. Because organisms use information--including DNA codes, gene expression, and chemical signaling--to construct, maintain, repair, and replicate themselves, it would seem only natural to use information-related ideas in our attempts to understand the general nature of living systems, the causality by which they operate, the difference between living and inanimate matter, and the emergence, in some biological species, of cognition, emotion, and language. And yet philosophe...
The Weird and the Eerie è l'ultimo libro pubblicato in vita da Mark Fisher, lo scrittore e critico culturale inglese che anche nel nostro paese sta ora raccogliendo grande interesse. Il suo Realismo capitalista ha generato un vivace dibattito e ha mostrato come Fisher sia una figura fondamentale per comprendere il presente. Ricordando l'amico, Simon Reynolds ha scritto: «Costruendo, con incomparabile rigore ed eloquenza, un ponte che collega estetica e politica, critica e attivismo, Fisher era davvero un intellettuale impegnato, potremmo dire persino: un John Berger post rave». Quest'ultima definizione è perfetta anche per inquadrare The Weird and the Eerie, dove s'indagano – tra lette...
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