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Germany’s Foreign Direct Investment in Times of Geopolitical Fragmentation
Global geopolitical tensions have risen in recent years, and European energy prices have been volatile following Russia’s invasion of Ukraine. Some analysts have suggested that these shifting conditions may significantly affect FDI both to and from Germany. To shed light on this issue and other factors affecting German FDI, we leverage two detailed and complementary FDI datasets to explore recent trends in German FDI and how it is affected by geopolitical tensions and energy prices. In doing so, we also develop a new measure of geopolitical alignment. Our main findings include the following: (i) the post-pandemic recovery in Germany’s inward and outward FDI has been weaker than in the US...
Cell Culture Techniques
This volume discusses the requirements, advantages, and limitations of studying cell culture. The chapters in this book cover topics such as in vitro blood-brain barrier functional assays in human iPSC-based models; neuron-glia interactions examines with in vitro co-culture; epigenetic changes in cultures neurons and astrocytes; rat brain slices; brain punching technique; and using microRNA for in vitro neurotoxicity testing and related disorders. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and cutting-edge, Cell Culture Techniques, Second Edition is a valuable resource for students and experiences researchers who are interested in learning more and making risk decisions in this evolving field.
Diabetic Foot Syndrome
This book provides a clear and integrated guide to the diagnostic pathways and therapeutic options available for the treatment of diabetic foot syndrome. The link between the location of the lesion and its potential causes are discussed in relation to its diagnosis, biomechanics, treatment and prognosis. Chapters covering interdigital lesions, the lateral side of the foot, torsion of the hallux, and the charcot foot are included. Diabetic Foot Syndrome: From Entity to Therapy aims to facilitate interdisciplinary understanding and is relevant to endocrinologists, as well as vascular and orthopedic surgeons.
The Blood-brain Barrier and Drug Delivery of the CNS
This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research.Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from nearly 40 international specialists in diverse fields, The Blood-Brain Barrier and Drug Delivery to the CNSassesses the properties of the blood-b...
On the Capacity to Absorb Public Investment: How Much is Too Much?
While expanding public investment can help filling infrastructure bottlenecks, scaling up too much and too fast often leads to inefficient outcomes. This paper rationalizes this outcome looking at the association between cost inflation and public investment in a large sample of road construction projects in developing countries. Consistent with the presence of absorptive capacity constraints, our results show a non-linear U-shaped relationship between public investment and project costs. Unit costs increase once public investment is close to 10% of GDP. This threshold is lower (about 7% of GDP) in countries with low investment efficiency and, in general, the effect of investment scaling up on costs is especially strong during investment booms.
This Time They Are Different
We study the long-run relationship between public debt and growth in a large panel of countries. Our analysis takes particular note of theoretical arguments and data considerations in modeling the debt-growth relationship as heterogeneous across countries. We investigate the issue of nonlinearities (debt thresholds) in both the cross-country and within-country dimensions, employing novel methods and diagnostics from the time-series literature adapted for use in the panel. We find some support for a nonlinear relationship between debt and long-run growth across countries, but no evidence for common debt thresholds within countries over time.
Regional Disparities, Growth, and Inclusiveness
We discuss regional disparities in economic performance and living standards. We first set out some key facts, and provide a conceptual framework to help analyze whether such disparities are efficient, or instead reflect market and/or policy failures. We examine whether policy attempts to reduce regional disparities necessarily involve a trade-off between equity and efficiency. We then investigate whether policymakers should focus on boosting the economic performance of lagging regions—or, conversely, accept the presence of regional disparities, and instead assist households in lagging regions through transfer payments, investments in education, health, and other basic services, and by facilitating out-migration.
Debriefing the President
Debriefing the President presents an astounding, candid portrait of one of our era’s most notorious strongmen. John Nixon, the first man to conduct a prolonged interrogation of Hussein after his capture, offers expert insight into the history and mind of America’s most enigmatic enemy. In December 2003, after one of the largest, most aggressive manhunts in history, US military forces captured Iraqi president Saddam Hussein near his hometown of Tikrit. Beset by body-double rumors and false alarms during a nine-month search, the Bush administration needed positive identification of the prisoner before it could make the announcement that would rocket around the world. At the time, John Nixo...
Public Value Management, Measurement and Reporting
This volume aims to shed light on how public service value is identified, managed, measured and reported. The chapters cover a range of topics, including theoretical reflections, practical case studies and empirical observations aimed at understanding the concept of public value.
