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The Bahía Blanca Estuary
The Bahía Blanca Estuary is one of the largest coastal systems in Atlantic South America. This mesotidal estuary, situated in a sharp transition between humid subtropical and semiarid climates, has a unique combination of large interannual climatic variations. The estuarine area encompasses roughly 2300 square kilometers and is composed of wide expanses of intertidal flats, salt marshes, and emerged islands, which create intricate landscape patterns. Natural environments in the estuary sustain a high concentration of marine and terrestrial species, including endemic, threatened, and endangered fish and shorebirds. Puerto Cuatreros, in the inner zone of the estuary, hosts a permanent marine ...
Metastases to the Central Nervous System, An Issue of Neurosurgery Clinics of North America
This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.
Tumor Immunology and Immunotherapy - Integrated Methods Part A
Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry, High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more. - Authored by leaders in the field of enzymology - Provides a comprehensiveness level of discussion on the field - Presents a highly specialized group of topics that delve deep into new updates and future prospects
Statistical Portfolio Estimation
The composition of portfolios is one of the most fundamental and important methods in financial engineering, used to control the risk of investments. This book provides a comprehensive overview of statistical inference for portfolios and their various applications. A variety of asset processes are introduced, including non-Gaussian stationary processes, nonlinear processes, non-stationary processes, and the book provides a framework for statistical inference using local asymptotic normality (LAN). The approach is generalized for portfolio estimation, so that many important problems can be covered. This book can primarily be used as a reference by researchers from statistics, mathematics, finance, econometrics, and genomics. It can also be used as a textbook by senior undergraduate and graduate students in these fields.
يوميات السرطان
«عندما أُصيبَت نانسي بالسرطان، لم نكُن نعلم ما إذا كان قد بدأ في مِبيضَيها، أم ثديَيها، أم رَحِمها، أم رئتَيها. وعلى مدى وقتٍ طويل (امتدَّ لأسابيع؛ إذ كانت عقارب الساعة تدور ببطء شديد)، لم نكُن نعرف أين كان ينمو، فكل ما عرفناه أنه كان يقذف بالخلايا السرطانية في جسدها.» يُعَدُّ هذا الكتاب محاوَلة من الكاتب الصحفي «جورج جونسون» لمعرفة أين نقف ضدَّ السرطان، وذلك بعد أن دفعته إصابةُ زوجت...
Crónicas del cáncer
Provocador, inteligente y conmovedor, Crónicas del cáncer pondrá a prueba todo lo que creías saber sobre la enfermedad. Desde el momento en que su esposa fue diagnosticada con esta terrible enfermedad, el reconocido divulgador científico George Johnson decidió que su aproximación debía ser la de comprender cómo y por qué se produce, porque para vencer a un enemigo lo mejor es tener un profundo conocimiento del mismo. Así rastreó los orígenes de la enfermedad a través de la paleontología hasta descubrir rasgos de tumores óseos parecidos a los que existen en la actualidad en algunos esqueletos de dinosaurios. También descubrió otras muestras de cáncer prehistórico en los restos de las diferentes razas de homínidos y en los yacimientos de necrópolis históricas. Se informó de las más punteras investigaciones y descubrió cómo el cáncer toma prestados los procesos naturales que intervienen en la cicatrización de una herida o el desarrollo de un embrión humano. El de Johnson es un planteamiento triple -histórico, científico y personal- y un viaje a través de una de las enfermedades más complicadas y universales que existen hoy en día.
The Cancer Chronicles
When the woman he loved was diagnosed with a metastatic cancer, science-writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is that a revolution is now under way – an explosion of new ideas about what cancer really is and where it comes from. He combs through the realms of epidemiology, clinical trials, laboratory experiments and scientific hypotheses, to reveal what we know and don’t know about cancer, showing why a cure remains such a slippery concept. His luminous accounts describe tumors that evolve like alien creatures inside the body, paleo-oncologist...
