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Cellular Dynamics within the Tumor Microenvironment
  • Language: en
  • Pages: 229

Cellular Dynamics within the Tumor Microenvironment

None

The Embryonic Protein Nodal Supports Metastatic Phenotypes in Breast Cancer
  • Language: en

The Embryonic Protein Nodal Supports Metastatic Phenotypes in Breast Cancer

  • Type: Book
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  • Published: 2012
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  • Publisher: Unknown

Metastasis is the process by which tumour cells disseminate to distant organ sites. Aberrant expression of stem cell-associated proteins within tumours is associated with metastasis and poor patient prognosis. One example of a stem cell factor that is associated with cancer progression is Nodal, a member of the TGF- superfamily. Nodal is normally limited to pluripotent stem cells during embryonic development, and to specialized dynamic adult tissue (such as the cycling endometrium), but is aberrantly re-expressed in multiple cancer types, including melanoma, glioma, prostate cancer, and pancreatic cancer. The central objective of this thesis is to determine the role of Nodal during various a...

The Tumor Microenvironment
  • Language: en
  • Pages: 417

The Tumor Microenvironment

This second edition provides update and new chapters detailing core and emerging in vitro and in vivo protocols. Chapters guide readers through cellular and molecular biology approaches, in vivo genetic approaches, various “omics”-based strategies, therapeutic strategies, and advanced techniques in the fields of tissue engineering and nanotechnology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, The Tumor Microenvironment: Methods and Protocols, Second Edition is a valuable resource for both novice and expert scientists in this developing field.

Cancer Immunotherapies: From Efficacy to Resistance Mechanisms
  • Language: en
  • Pages: 470

Cancer Immunotherapies: From Efficacy to Resistance Mechanisms

Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.

Nanoparticles in Cancer Therapy
  • Language: en
  • Pages: 345

Nanoparticles in Cancer Therapy

  • Type: Book
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  • Published: 2024-11-08
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  • Publisher: CRC Press

This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...

The Molecular Basis of Cancer
  • Language: en
  • Pages: 1040

The Molecular Basis of Cancer

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip...

Krebs - Lifestyle und Umweltfaktoren als Risiko
  • Language: de
  • Pages: 180

Krebs - Lifestyle und Umweltfaktoren als Risiko

Renommierte Heidelberger Wissenschaftler haben in diesem Buch zusammengetragen, was heute über Krebserkrankungen und ihre Ursachen bekannt ist. Lediglich 5 bis 10% aller Krebserkrankungen werden durch vererbte Gendefekte verursacht. Epidemiologische und experimentelle Daten aus wissenschaftlichen Studien und Hochrechnungen zeigen, wie sehr das Erkrankungsrisiko durch die eigene moderne Lebensweise beeinflusst wird. Die Autoren haben sich zum Ziel gesetzt, diffusen Ängsten und gefährlichem Halbwissen wissenschaftlich valides Wissen entgegenzusetzen und diese Daten und Fakten verständlich und unterhaltsam zu präsentieren. Das Buch richtet sich an alle medizinisch Interessierten, Betroffene und Angehörige.

Wildlife Review
  • Language: en
  • Pages: 430

Wildlife Review

  • Type: Book
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  • Published: 1995
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  • Publisher: Unknown

None

Pathology of Wildlife and Zoo Animals
  • Language: en
  • Pages: 1424

Pathology of Wildlife and Zoo Animals

Pathology of Wildlife and Zoo Animals is a comprehensive resource that covers the pathology of wildlife and zoo species, including a wide scope of animals, disease types and geographic regions. It is the definitive book for students, biologists, scientists, physicians, veterinary clinicians and pathologists working with non-domestic species in a variety of settings. General chapters include information on performing necropsies, proper techniques to meet the specialized needs of forensic cases, laboratory diagnostics, and an introduction into basic principles of comparative clinical pathology. The taxon-based chapters provide information about disease in related groups of animals and include ...

Financial Contagion
  • Language: en
  • Pages: 570

Financial Contagion

"Financial Contagion: The Viral Threat to the Wealth of Nations covers a lot of territory. It is, of course, terribly important to analyze case histories to discover potential triggers, mechanisms of transmission, and viable ways to contain the damage of financial contagion. The problem is, as these articles amply demonstrate, that there’s always a new virus or a mutation of a former one lurking in some corner of the financial world. We don’t know what it is or where it is. And, even if we had some inkling, there’s almost never enough time to develop a financial flu shot." --SeekingAlpha.com The latest insights on financial contagion and how both nations and investors can effectively d...