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This second edition provides update and new chapters detailing core and emerging in vitro and in vivo protocols. Chapters guide readers through cellular and molecular biology approaches, in vivo genetic approaches, various “omics”-based strategies, therapeutic strategies, and advanced techniques in the fields of tissue engineering and nanotechnology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, The Tumor Microenvironment: Methods and Protocols, Second Edition is a valuable resource for both novice and expert scientists in this developing field.
Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...
2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip...
Tutti gli organismi viventi sono attraversati dall'elettricità: per quanto possa sembrarci strano, muscoli, ossa, pelle e nervi possiedono una carica in grado di trasmettere messaggi e impulsi ad altri organi e di riceverli dall'ambiente circostante. Noi siamo elettrici ci porta a scoprire questo innovativo campo di ricerca, mostrandoci in che modo potrebbe rivoluzionare la medicina e il nostro intero futuro. La bioelettricità è più antica del sistema nervoso e sostiene ogni nostra azione, dalla più semplice alla più complessa. La storia del suo studio è però travagliata: già nel Settecento Luigi Galvani aveva dimostrato la presenza di potenziale elettrico all'interno dei tessuti an...
Renommierte Heidelberger Wissenschaftler haben in diesem Buch zusammengetragen, was heute über Krebserkrankungen und ihre Ursachen bekannt ist. Lediglich 5 bis 10% aller Krebserkrankungen werden durch vererbte Gendefekte verursacht. Epidemiologische und experimentelle Daten aus wissenschaftlichen Studien und Hochrechnungen zeigen, wie sehr das Erkrankungsrisiko durch die eigene moderne Lebensweise beeinflusst wird. Die Autoren haben sich zum Ziel gesetzt, diffusen Ängsten und gefährlichem Halbwissen wissenschaftlich valides Wissen entgegenzusetzen und diese Daten und Fakten verständlich und unterhaltsam zu präsentieren. Das Buch richtet sich an alle medizinisch Interessierten, Betroffene und Angehörige.
A BEST BOOK OF 2023 FOR THE TELEGRAPH, FINANCIAL TIMES, NEW SCIENTIST AND STYLIST A NEXT BIG IDEA CLUB MUST READ 2023 Discover the next frontier of scientific understanding: your body’s electrome. Every cell in your body – bones, skin, nerves, muscle – has a voltage, like a tiny battery. This bioelectricity is why your brain can send signals to your body, why it develops and how it heals itself. In We Are Electric, award-winning science writer Sally Adee explores the colourful history of bioelectricity and journeys into the remarkable future of the discipline, through today’s laboratories where real-world medical applications are being developed.
A dictionary with more than 40,000 entries which was a primary reference source for scholars and writers of the 18th and 19th century.
This pocket-sized reference contains approximately 4,500 common Italian slang words and colloquial expressions not usually found in standard Italian-English dictionaries. Entries contain grammatical information, the definition in English, a sentence or phrase in Italian to illustrate usage, and an English translation of the example using, where applicable, a corresponding English slang expression. Gobetti is program associate at the Center for European Studies, the U. of Michigan. Annotation copyrighted by Book News, Inc., Portland, OR.