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The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to the development of new-targeted therapies and the optimization of therapeutics. Therefore, metabolomic research may be more clinically translatable than other omics approaches, since metabolites are closely related to the phenotype and the metabolome is sensitive to many factors. Metabolomics seems promising to identify key metabolic pathways characterizing features of pathological and physiological states. Thus, knowing that tumor metabolism markedly differs from the metabolism of normal cells, the use of metabolomics is ideally suited for biomarker research. Some works have already focused on the application of metabolomic approaches to different cancers, namely lung, breast and liver, using urine, exhaled breath and blood. In this Special Issue we contribute to a more complete understanding of cancer disease using metabolomics approaches.
Women and men have probably never been concerned as much by their health as during this COVID-19 pandemic. In this context, lifestyle habits continue to be promoted as allies for daily prevention against diseases. This is valid also for metabolic diseases, among which many affect the liver and are risk factors for aggravating the disease course of COVID-19. In fact, liver diseases are currently a major global health problem. There is a huge range of liver diseases and non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic condition, which in some patients progresses to cirrhosis and liver cancer. Currently, substantial efforts are being made to better understand NAFLD, ...
Gas Chromatography involves the study of various vaporizable molecules in chemistry and the other related research fields. This analytical method has a number of features and advantages that make it an extremely valuable tool for the identification, quantification and structural elucidation of organic molecules. This book provides detailed gas chromatography information to applications of biochemicals, narcotics and essential oils. The details of the applications were briefly handled by the authors to increase their comprehensibility and feasibility. This guide should be certainly valuable to the novice, as well as to the experienced gas chromatography user who may not have the enough experience about the specific applications covered in this book. We believe this book will prove useful in most laboratories where modern gas chromatography is practiced.
Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
This comprehensive book offers a fascinating exploration of the dynamic relationships that exist between plants and fungi, shedding light on the latest advancements in research and opening a window into the remarkable potential of these partnerships. From mycorrhizal networks that enhance plant nutrient uptake to endophytic fungi that fortify plant defences and produce bioactive secondary metabolites of medicinal importance, this book unravels the multifaceted role that fungi play in shaping the health and resilience of plant ecosystems. Whether you're a seasoned mycologist, a curious botanist, or simply intrigued by the wonders of nature's collaborations, this book provides a captivating journey through the diverse realms of plant-fungi interactions, offering a glimpse into the promising prospects that these partnerships hold for the future exploration and application in areas ranging from sustainable agriculture to drug discovery, ecological restoration and beyond.
This book gathers peer-review contributions to the 5th International Workshop on Gerontechnology, IWoG 2022, held on November 17-18, 2022, in Évora, Portugal, and in Caceres, Spain. They report on cutting-edge technologies and optimized workflows for promoting active aging and assisting older adults at home, as well as in healthcare centers. They discuss the main challenges in the development, use and delivery of health care services and technologies. Besides proposing solutions for improving monitoring and management of health parameters and age-related diseases, the chapters also describe approaches for helping seniors in their daily tasks and facilitating their communication and integration with assistive technologies. All in all, this book provides health professionals, researchers, and service providers with extensive information on the latest trends in the development and application of gerontechnology, with a special emphasis on improving quality of life and social integration of the elderly.
This informative book discusses the various spectroscopic techniques applied in the analysis of food and beverages. The respective chapters cover techniques such as Laser-Induced Breakdown Spectroscopy (LIBS), FTIR spectroscopy, Electron Spin Resonance (ESR) spectroscopy and Thermoluminescence. The book also presents artificial intelligence applications that can be used to enhance the spectral data analysis experience in food safety and quality analysis. Given its scope, the book will appeal to novice researchers and students in the area of food science. It offers an equally exciting read for food scientists and engineers working in the food industry.
This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Nat...
The issue concentrates on the history and current production practices unique to the specialty wines. This includes fortified wines, such as ports, sherries, sparkling wines, and distinctive table wines, such as vin santo, botrytised, and carbonic maceration wines. - The latest important information for food scientists and nutritionists - Peer-reviewed articles by a panel of respected scientists - The go-to series since 1948