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A Short History of the Drug Receptor Concept
The concept of specific receptors for drugs, hormones and transmitters lies at the very heart of biomedicine. This book is the first to consider the idea from its 19th century origins in the work of John Newport Langley and Paul Ehrlich, to its development of during the 20th century and its current impact on drug discovery in the 21st century.
Epitope Recognition Since Landsteiner’s Discovery
Karl Landsteiner is best known for his discovery of the human blood goups. The revolutionary discoveries of this brilliant scientist in other fields have not received the recognition they deserve. His demonstration that poliomyelitis is transmissable showed the way of modern virology. His studies opening the field for epitope recognition, which he himself considered his main achievement, laid the foundation for research ongoing in our days. This book with its outstanding contributors is but a small tribute to this visionary scientist.
Flesh and Blood
Organ transplantation is one of the most dramatic interventions in modern medicine. Since the 1950s thousands of people have lived with 'new' hearts, kidneys, lungs, corneas, and other organs and tissues transplanted into their bodies. From the beginning, though, there was simply a problem: surgeons often encountered shortages of people willing and able to give their organs and tissues. To overcome this problem, they often brokered financial arrangements. Yet an ethic of gift exchange coexisted with the 'commodification of the body'. The same duality characterized the field of blood transfusion, which was essential to the development of modern surgery.This book will be the first to bring tog...
Biomedicine in the Twentieth Century
." . . based on a conference that was held at the National Institutes of Health in December 2005 to promote historical research on biomedical science in the twentieth century"--p. ix.
The Oxford Handbook of the History of Eugenics
Eugenic thought and practice swept the world from the late nineteenth to the mid-twentieth century in a remarkable transnational phenomenon. Eugenics informed social and scientific policy across the political spectrum, from liberal welfare measures in emerging social-democratic states to feminist ambitions for birth control, from public health campaigns to totalitarian dreams of the "perfectibility of man." This book dispels for uninitiated readers the automatic and apparently exclusive link between eugenics and the Holocaust. It is the first world history of eugenics and an indispensable core text for both teaching and research. Eugenics has accumulated generations of interest as experts at...
A Traffic of Dead Bodies
A Traffic of Dead Bodies enters the sphere of bodysnatching medical students, dissection-room pranks, and anatomical fantasy. It shows how nineteenth-century American physicians used anatomy to develop a vital professional identity, while claiming authority over the living and the dead. It also introduces the middle-class women and men, working people, unorthodox healers, cultural radicals, entrepreneurs, and health reformers who resisted and exploited anatomy to articulate their own social identities and visions. The nineteenth century saw the rise of the American medical profession: a proliferation of practitioners, journals, organizations, sects, and schools. Anatomy lay at the heart of t...
The American Religious Debate Over Birth Control, 1907-1937
The ongoing debates on the morality of artificial birth control sparked a heated public debate in the early twentieth century in an already religiously fragmented United States. Many denominations took part in the deliberations both publicly and privately. In examining the ideas about contraception and birth control at that time, this book considers the cultural environment, religion and its connection to the roots of birth control, the questioning of religious doctrine, the Protestants' view of birth control, the Lambeth conferences of 1930, the influence of conservatives, and the influence of Catholics. Also discussed is the historical context of fundamentalists versus modernists, neo-Malthusianism, eugenics, immigration, the movement for legalization organized by Margaret Sanger, and how the Catholic Church came to lead religious resistance to artificial birth control.
Influenza
In 1976, the outbreak of a new strain of swine flu at the Fort Dix, New Jersey, army base prompted an unprecedented inoculation campaign. Some forty-two million Americans were vaccinated as the National Influenza Immunization Program hastened to prevent a pandemic, while the World Health Organization (WHO) took a wait-and-see approach. Fortunately, the virus did not spread, and only one death occurred. But instead of being lauded, American actions were subsequently denounced as a "fiasco" and instigator of mass panic. In Influenza, George Dehner examines the wide disparity in national and international responses to influenza pandemics, from the Russian flu of 1889 to the swine flu outbreak i...
Racializing the Soldier
Racializing the Soldier explores the impact of racial beliefs on the formation and development of modern armed forces and the ways in which these forces have been presented and historicized from a global perspective. With a wide geographical and temporal spread, the collection looks at the disparate ways that race has influenced military development. In particular, it explores the extent to which ideas of racial hierarchy and type have conditioned thinking about what kinds of soldiers should be used and in what roles. This volume offers a highly original military, social and cultural history, questioning the borders both of racialization and of the military itself. It considers the extent to...
Clinical Immuno-Oncology - E-Book
Offering focused, practical, and up-to-date content on immunotherapies used to treat a wide variety of cancer types, Clinical Immuno-Oncology covers the basic cellular and molecular mechanisms involved in cancer initiation and progression. The text reviews the development of tumor specific antigens and the challenges of developing cancer immunotherapies. Every effort is made to relate the fundamental aspects of host immunity to the efficacy of current immunotherapies and how they work in conjunction with the immune system to combat cancer. This foundational resource explains the basics of cancer immunotherapy, discusses best practices, and provides recommendations from experienced clinicians...
