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CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, ...
The two-volume set LNCS 3522 and 3523 constitutes the refereed proceedings of the Second Iberian Conference on Pattern Recognition and Image Analysis, IbPRIA 2005, held in Estoril, Portugal in June 2005. The 170 revised full papers presented were carefully reviewed and selected from 292 submissions. The papers are organized in topical sections on computer vision, shape and matching, image and video processing, image and video coding, face recognition, human activity analysis, surveillance, robotics, hardware architectures, statistical pattern recognition, syntactical pattern recognition, image analysis, document analysis, bioinformatics, medical imaging, biometrics, speech recognition, natural language analysis, and applications.
Rising densities of human settlements, migration and transport to reduce distances to market, and specialization and trade facilitated by fewer international divisions are central to economic development. The transformations along these three dimensions density, distance, and division are most noticeable in North America, Western Europe, and Japan, but countries in Asia and Eastern Europe are changing in ways similar in scope and speed. 'World Development Report 2009: Reshaping Economic Geography' concludes that these spatial transformations are essential, and should be encouraged. The conclusion is not without controversy. Slum-dwellers now number a billion, but the rush to cities continues...
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The two-volume set LNCS 3522 and 3523 constitutes the refereed proceedings of the Second Iberian Conference on Pattern Recognition and Image Analysis, IbPRIA 2005, held in Estoril, Portugal in June 2005. The 170 revised full papers presented were carefully reviewed and selected from 292 submissions. The papers are organized in topical sections on computer vision, shape and matching, image and video processing, image and video coding, face recognition, human activity analysis, surveillance, robotics, hardware architectures, statistical pattern recognition, syntactical pattern recognition, image analysis, document analysis, bioinformatics, medical imaging, biometrics, speech recognition, natural language analysis, and applications.