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Introduction to Single Cell Omics
Single-cell omics is a progressing frontier that stems from the sequencing of the human genome and the development of omics technologies, particularly genomics, transcriptomics, epigenomics and proteomics, but the sensitivity is now improved to single-cell level. The new generation of methodologies, especially the next generation sequencing (NGS) technology, plays a leading role in genomics related fields; however, the conventional techniques of omics require number of cells to be large, usually on the order of millions of cells, which is hardly accessible in some cases. More importantly, harnessing the power of omics technologies and applying those at the single-cell level are crucial since...
Cytogenetics and Molecular Cytogenetics
Genomic technologies provide the means of diagnosis and management of many human diseases. Without insights from cytogenetics, correct interpretation of modern high-throughput results is difficult, if not impossible. This book summarizes applications of cytogenetics and molecular cytogenetics for students, clinicians and researchers in genetics, genomics and diagnostics. The book combines the state-of-the-art knowledge and practical expertise from leading researchers and clinicians and provides a comprehensive overview of current medical and research applications of many of these technologies. KEY FEATURES • Provides clear summaries of fluorescence in situ hybridization technologies and others • Comprehensively covers established and emerging methods • Chapters from an international team of leading researchers • Useful for students, researchers and clinicians
Developmental Disabilities
Although various developmental disabilities affecting children and adults might have different pathogeneses, underlying mechanisms, and clinical presentations, the current books emphasizes the fact that there are numerous commonalities in methods of understanding, clinical diagnosis, and handling of behavioral abnormalities in affected individuals. For instance, understanding sexual maturation and its consequences in people with intellectual disability would certainly present a path to better understanding of the differences with controls and more effective handling of the unwanted consequences in people affected.
Advanced Mechanical Engineering II
Selected, peer reviewed papers from the 2012 International Conference on Advanced Mechanical Engineering (AME 2012), July 7-8, 2012, Wuhan, China
The AGT Cytogenetics Laboratory Manual
Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic seque...
Review of Progress in Quantitative Nondestructive Evaluation
These Proceedings, consisting of Parts A and B, contain the edited versions of most of the papers presented at the annual Review of Progress in Quantitative Nondestructive Evaluation held at Snowmass Village, Colorado, on July 31 to August 4, 1994. The Review was organized by the Center for NDE at Iowa State University, in cooperation with the Ames Laboratory of the US DOE, the Materials Directorate of the Wright Laboratory, Wright-Patterson Air Force Base, the American Society of Nondestructive Testing, the Department of Energy, the National Institute of Standards and Technology, the Federal Aviation Administration, the National Science Foundation Industry/University Cooperative Research Ce...
Hematology E-Book
Gain a foundational understanding of complex hematology concepts with this thoroughly revised text. Hematology: A Pathophysiologic Approach, 2nd Edition, a volume in the?Mosby Physiology Series,?explains the fundamentals of this multi-faceted area in a clear and concise manner. It offers masterful explanations of hematopoiesis, immunology, hemostasis, hemoglobinopathy, metabolic disorders, genetics, and neoplasia from S. David Hudnall, MD, Professor Emeritus of Pathology and Laboratory Medicine at Yale University School of Medicine. Prof. Hudnall, who has practiced laboratory hematology and hematopathology for more than 30 years, has taught the principles of hematology to thousands of pre-me...
Gestational Trophoblastic Disease
In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations. Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent ad...
Fatigue and Fracture, 1996
The second of two volumes on the subject containing papers from a symposium of the July 1996 meeting. Thirty papers are arranged in four sections on new areas of fracture mechanics; material fracture toughness; failure assessment diagram method user experience (with four application-type papers); an
