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Diperts in America
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Influence of the COVID-19 Pandemic on Musculoskeletal Complaints and Psychological Well-being of Employees in Public Services -- a Cohort Study
Abstract: Background: The COVID-19 pandemic resulted in unprecedented restrictions on public and private life. The aim of the study was to investigate the impact of the COVID-19 pandemic on the physical and mental health of employees in the public sector, especially patient-related professions. Methods: For the data collection in summer 2021, an online questionnaire was used. Compared to a pre-pandemic point of time, the prevalence, frequency, and intensity of musculoskeletal pain, mental well-being, health status, and quality of life were recorded. Results: The questionnaire was completed by 1678 employees (f: 1045, m: 617). A total of 1504 employees (89.6%) were affected by complaints. Compared to before the pandemic, the prevalence and intensity of musculoskeletal complaints and psychological distress increased significantly. Patient-related professions (n = 204) showed significantly higher levels of stress and discomfort in several aspects (p
At a Snail's Pace
Adam Schneck emigrated to the colonies in 1749 and settled in the Lehigh Valley of eastern Pennsylvania. He married Catharina and they were parents to six children. Their eldest son, Johann Peter (b.1755) married Magdalena, the daughter of Hans Niccolaus and Maria Catharina Hertzog. They were parents to nine children. Their son Peter Schneck (1779-1851) married (1) Maria Catharina Baer, the daughter of Johann Adam Baer and Anna Margaretha Peter and lived in Whitehall Twp., Northampton Co., PA. Daniel Schneck (b.1807) the second son of Peter Schneck and Cathrina Baer of Pinegrove Twp., Berks Co., PA married Magdalena Stein, daugher of Johann Georg Stein and Catharina Gebhard. They were the parents of four children. Solomon Schneck (1809-1889) was the third son of Peter Schneck and Catharina Baer of Pinegrove Twp., Berks Co., PA. He married Anna Maria Reichert, daughter of Carl and Maria Sara Reichert. They were the parents of nine children.
Beneficial Long Term Effect of a Phosphodiesterase-5-inhibitor in Cirrhotic Portal Hypertension
Abstract: Non-selective beta-blockers are the mainstay of medical therapy for portal hypertension in liver cirrhosis. Inhibitors of phosphodiesterase-5 (PDE-5-inhibitors) reduce portal pressure in the acute setting by > 10% which may suggest a long-term beneficial effect. Currently, there is no available data on long-term treatment of portal hypertension with PDE-5-inhibitors. This case of a patient with liver cirrhosis secondary to autoimmune liver disease with episodes of bleeding from esophageal varices is the first documented case in which a treatment with a PDE-5-inhibitor for eight years was monitored. In the acute setting, the PDE-5- inhibitor Vardenafil lowered portal pressure by 13%. The portal blood flow increased by 28% based on Doppler sonography and by 16% using MRI technique. As maintenance medication the PDE-5-inhibitor Tadalafil was used for eight consecutive years with comparable effects on portal pressure and portal blood flow. There were no recurrence of bleeding and no formation of new varices. Influencing the NO-pathway by the use of PDE-5 inhibitors may have long-term beneficial effects in compensated cirrhosis
Close Relationship Between Systemic Arterial and Portal Venous Pressure in an Animal Model with Healthy Liver
Abstract: It is unclear to what extent systemic arterial blood pressure influences portal pressure. This relationship is clinically important as drugs, which are conventionally used for therapy of portal hypertension, may also influence systemic arterial blood pressure. This study investigated the potential correlation between mean arterial (MAP) and portal venous pressure (PVP) in rats with healthy livers. In a rat model with healthy livers, we investigated the effect of manipulation of MAP on PVP. Interventions consisted of 0.9% NaCl (group 1), 0.1 mg/kg body weight (bw) Sildenafil (low dose), an inhibitor of phosphodiesterase-5 (group 2), and 1.0 mg/kg bw Sildenafil (high dose, group 3) i...
Trends in the Numbers of SARS-CoV-2 Infections Among Students: a Prospective Cohort Study Comparing Students in Sports Boarding Schools with Students in Day Schools During Early COVID-19 Pandemic
Abstract: Introduction: During the first months of the COVID pandemic it emerged that facilities where people gather or live together in cohorts, such as nursing homes or schools, were particularly at high risk for becoming hotspots of virus transmission. German political and health institutions responded with far-reaching interventions and preventive strategies to protect the population from infection with SARS-CoV-2. In this context, it remains unclear whether boarding schools for sports particularly pose a risk of infection to their residents. Methods: In a single-center prospective cohort study, numbers of SARS-CoV-2 infections of students in sports boarding schools (n = 11) vs. students...
