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Pharmacology of Intestinal Permeation I
  • Language: en
  • Pages: 719

Pharmacology of Intestinal Permeation I

The intestine, particularly the small bowel, represents a large surface (in the adult 2 human approximately 200m ) through which the body is exposed to its environment. A vigorous substrate exchange takes place across this large surface: nutrients and xenobiotics are absorbed from the lumen into the bloodstream or the lymph, and simultaneously, the same types of substrate pass back into the lumen. The luminal surface of the intestine is lined with a "leaky" epithelium, thus the passage of the substrates, in either direction, proceeds via both transcellular and intercellular routes. Simple and carrier-mediated diffusion, active transport, pinocytosis, phagocytosis and persorption are all invo...

Pathology of the Nucleus
  • Language: en
  • Pages: 491

Pathology of the Nucleus

New techniques make it possible for investigators to examine and sometimes quantify various aspects of nuclear morphology and function; now they can derive clinically and biologically useful information about the nucleus. This book draws together a series of techniques which have been successfully applied to the study of the nucleus of tumour cells. These are of fundamental importance to researchers in tumour histopathology and medical oncology. Detailed reviews are given of various aspects of the morphology, ploidy and karyotypic status and function of the nuclei in the cells of tumours and preneoplastic lesions. Topics covered include nuclear morphology in tumour diagnosis, the ultrastructure of the nucleus, karyotypic analyses of solid tumours, flow cytometric assessment of nuclear ploidy and other parameters, histomorphometry of the nucleus, and in situ hybridisation.

Strings of Connectedness
  • Language: en
  • Pages: 361

Strings of Connectedness

  • Type: Book
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  • Published: 2015-09-18
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  • Publisher: ANU Press

For nearly four decades, Ian Keen has been an important, challenging, and engaging presence in Australian anthropology. Beginning with his PhD research in the mid-1970s and through to the present, he has been a leading scholar of Yolngu society and culture, and has made lasting contributions to a range of debates. His scholarly productivity, however, has never been limited to the Yolngu, and he has conducted research and published widely on many other facets of Australian Aboriginal society: on Aboriginal culture in ‘settled’ Australia; comparative historical work on Aboriginal societies at the threshold of colonisation; a continuing interest in kinship; ongoing writing on language and s...

Representing Humanity in the Age of Enlightenment
  • Language: en
  • Pages: 254

Representing Humanity in the Age of Enlightenment

  • Type: Book
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  • Published: 2015-10-06
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  • Publisher: Routledge

The Enlightenment era saw European thinkers increasingly concerned with what it meant to be human. This collection of essays traces the concept of ‘humanity’ through revolutionary politics, feminist biography, portraiture, explorer narratives, libertine and Orientalist fiction, the philosophy of conversation and musicology.

Pharmacology of Intestinal Permeation II
  • Language: en
  • Pages: 600

Pharmacology of Intestinal Permeation II

The intestine, particularly the small bowel, represents a large surface (in the adult 2 human approximately 200 m ) through which the body is exposed to its environ ment. A vigorous substrate exchange takes place across this large surface: nutrients and xenobiotics are absorbed from the lumen into the bloodstream or the lymph, and simultaneously, the same types of substrate pass back into the lumen. The luminal surface of the intestine is lined with a "leaky" epithelium, thus the passage of the substrates, in either direction, proceeds via both transcellular and intercellular routes. Simple and carrier-mediated diffusion, active transport, pinocytosis, phagocytosis and persorption are all in...

Ethnomusicology
  • Language: en
  • Pages: 698

Ethnomusicology

  • Type: Book
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  • Published: 2013-09-05
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  • Publisher: Routledge

Ethnomusicology: A Contemporary Reader is designed to supplement a textbook for an introductory course in ethnomusicology. It offers a cross section of the best new writing in the field from the last 15-20 years. Many instructors supplement textbook readings and listening assignments with scholarly articles that provide more in-depth information on geographic regions and topics and introduce issues that can facilitate class or small group discussion. These sources serve other purposes as well: they exemplify research technique and format and serve as models for the use of academic language, and collectively they can also illustrate the range of ethnographic method and analytical style in the discipline of ethnomusicology. Ethnomusicology: A Contemporary Reader serves as a basic introduction to the best writing in the field for students, professors, and music professionals. It is perfect for both introductory and upper level courses in world music.

Arabic Instruction in Israel
  • Language: en
  • Pages: 195

Arabic Instruction in Israel

  • Type: Book
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  • Published: 2017-07-10
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  • Publisher: BRILL

In Arabic Instruction in Israel Allon J. Uhlmann confronts two conundrums, namely the persistently poor level of Arabic proficiency among Jewish Arabic students and teachers, and the traumatic alienation of Arab students by university Arabic grammar instruction. These are not aberrations but rather direct, albeit unintended, systemic consequences of the field of Arabic instruction, where Jewish students encounter Arabic as a dead, hostile language; Jewish hegemony devalues native Arabic proficiency; and Arab students are locked into a fractured educational trajectory – encountering two alienating and mutually unintelligible grammars of Arabic at school and at university. By tracing systemic variabilities in cognition and learning Uhlmann exposes hitherto misrecognised dynamics that hinder Arabic instruction in Israel, thereby offering new avenues for possible change.

Methods for Studying Mononuclear Phagocytes
  • Language: en
  • Pages: 1048

Methods for Studying Mononuclear Phagocytes

  • Type: Book
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  • Published: 2012-12-02
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  • Publisher: Elsevier

Methods for Studying Mononuclear Phagocytes is a practical guide to the study of mononuclear phagocytes that brings together various well-established and useful methods for examining these cells. The technical protocols have been made detailed, specific, practical, and inclusive of the necessary mystique for immediate and direct application in the laboratory. The book is divided into 11 parts arranged according to the sequence of steps that would generally be followed to study a given population of mononuclear phagocytes: (I) methods for obtaining and culturing populations of human and animal mononuclear phagocytes; (II) methods for separating populations of leukocytes to enrich or deplete t...

Reaction Patterns of the Lymph Node
  • Language: en
  • Pages: 298

Reaction Patterns of the Lymph Node

Due to the topology and structure of the lymph nodes, their role in the pathogenesis and development of diseases is a very special one. Each organ and even each organ-related region of the body has its own group of lymph nodes, specific topological reactions, such as in circumscribed inflammation or in the metastatic spread of malignant tumors. On the other hand, all the lymph nodes of an organism join in a uniform function effected by highly differentiated structures. Volume 84 of Current Topics in Pathology presents our current knowledge about the structure and reaction patterns of this "sec ondary" lymphoid organ. Despite our original intention to publish all the contributions in one book, it became necessary to divide them: Part 1 focuses on the involved nodal compartments, cell types, and functions, while Part 2 describes their reactions in inflammatory, neo plastic, and immune-deficient diseases. Even with the cooperation of more than 30 authors, the coverage cannot be exhaustive. The scope of both parts is limited to those reactions that can be described by direct and indirect morphological methods, including modern tech niques such as immune electron microscopy.