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Biology of Poxviruses
  • Language: en
  • Pages: 202

Biology of Poxviruses

This volume, Biology of Poxviruses, marks our debut as editors of this well known series. We plan to continue the tradition of providing a forum for exten sive, critical reviews of individual virus groups, as exemplified by the present volume. But the pace of discovery is accelerating so rapidly that we feel the need to offer an additional format: volumes that contain collections of shorter, topical reviews on a group of related subjects. Such collections might cut across con ventional boundaries between virus groups, dealing, as an example, with a partic ular aspect of virus-cell interaction. Admittedly, this new format stretches the term "monograph" beyond the accepted definition, but we believe that we should pay that price to maintain the usefulness of the series as a medium of scientific communication. Whenever possible, we will enlist the aid of deputy editors to bring such col lections to fruition. As in the past, the editors and the publisher will welcome suggestions for topics and contributions.

Poxviridae Infections: Advances in Research and Treatment: 2011 Edition
  • Language: en
  • Pages: 38

Poxviridae Infections: Advances in Research and Treatment: 2011 Edition

Poxviridae Infections: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Poxviridae Infections in a compact format. The editors have built Poxviridae Infections: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Poxviridae Infections in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Poxviridae Infections: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Poxviridae Research and Treatment: 2011 Edition
  • Language: en
  • Pages: 26

Advances in Poxviridae Research and Treatment: 2011 Edition

Advances in Poxviridae Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Poxviridae in a compact format. The editors have built Advances in Poxviridae Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Poxviridae in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Poxviridae Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Poxviruses
  • Language: en
  • Pages: 447

Poxviruses

This monograph provides a comprehensive review of the poxvirus family with a particular emphasis on current developments. It includes the latest insights into poxviral molecular biology, diagnosis, therapy, vaccine development and the beneficial exploitation of these viruses in biomedical research. Each chapter is written by a leader in the field, and the book includes historical perspectives and summaries of recent advances in the field.

Poxviridae Infections—Advances in Research and Treatment: 2012 Edition
  • Language: en
  • Pages: 61

Poxviridae Infections—Advances in Research and Treatment: 2012 Edition

Poxviridae Infections—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Poxviridae Infections in a concise format. The editors have built Poxviridae Infections—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Poxviridae Infections in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Poxviridae Infections—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Recombinant Poxviruses
  • Language: en
  • Pages: 360

Recombinant Poxviruses

  • Type: Book
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  • Published: 1992-05-27
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  • Publisher: CRC Press

Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines. The book considers a wide range of issues involved in producing new genetically engineered live vaccines, such as efficacy, safety, stability, cost, host range, immune response, immunization route, use of multivalent vaccines, and need for revaccination. The opening chapter describes the origin of vaccinia virus, its use to eradicate smallpox, and the pathogenesis of poxvirus infections. Subsequent chapters examine the molecular biology of poxviruses, methods of constructing vaccinia virus recombinants, and applications; the use and immune responses induced by poxvirus recombinants as live vaccines; and the important issues of the safety and immunogenicity of vaccinia virus. The book's final two chapters report the progress that has been made developing avipoxviruses and parapoxviruses as candidate recombinant vaccines. Recombinant Poxviruses will be a welcome addition to the bookshelves of virologists, microbiologists, infectious disease specialists, and veterinarians.

Vaccinia Virus and Poxvirology
  • Language: en
  • Pages: 402

Vaccinia Virus and Poxvirology

The Right Book at the Right Time The poxviruses comprise a family of complex DNA viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. Of the eight recognized g- era of vertebrate poxviruses, those belonging to the orthopoxvirus genus have been most intensively studied. This group includes variola virus, the agent of smallpox, as well as cowpox virus and vaccinia virus. Jenner’s original sma- pox vaccine, described in 1798, consisted of live cowpox virus, but vaccinia virus later replaced it (1). There has been speculation as to the origin of v- cinia virus; the most likely idea is that it is a separate species, possibly ori- nally isolated from a horse, and is now e...

Orthopoxviruses Pathogenic for Humans
  • Language: en
  • Pages: 442

Orthopoxviruses Pathogenic for Humans

Orthopoxviruses Pathogenic for Humans covers those viruses capable of causing disease in man, including monkeypox, smallpox, cowpox, and vaccinia. The coverage of each virus is comprehensive, covering the biology, molecular biology, and ecology of the virus as well as the clinical and epidemiological aspects of these viruses in humans and animals. In addition, this volume highlights developments in genetic engineering that are paving the way for potential therapeutic treatments of these viruses.

The Orthopoxviruses
  • Language: en
  • Pages: 443

The Orthopoxviruses

  • Type: Book
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  • Published: 2012-12-02
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  • Publisher: Elsevier

The Orthopoxviruses presents knowledge and comprehensive and integrated picture of orthopoxviruses. The book looks into the molecular biology of this genusof viruses, particularly, the structure and chemical composition of the virion, replication, morphogenesis, pathogenesis, pathology, and immunology of this virus' infections. It also elucidates the global spread, control, and eradication of smallpox. Additionally, the book describes a potentially important use of vaccinia virus, namely, its use as a vector for genes from other viruses, bacteria, or protozoa that specify antigens important in stimulating the production of a protective immune response. Such comprehensive account of all aspects of the biology of all known species of orthopoxviruses will be valuable to molecular biologists, virologists, immunologists, pathologists, and researchers in the veterinary sciences.

Assessment of Future Scientific Needs for Live Variola Virus
  • Language: en
  • Pages: 126

Assessment of Future Scientific Needs for Live Variola Virus

In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. In 1986, WHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus, one at the Centers for Disease Control and Prevention and the other at the VECTOR laboratory in Siberia. In June 1999, WHO decided to delay the destruction of these stocks. Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies. What further benefits, if any, would likely be gained through the use of variola in research and development efforts related to agent detection, diagnosis, prevention, and treatment. What unique potential benefits, if any, the study of variola would have in increasing our fundamental understanding of the biology, host-agent interactions, pathogenesis, and immune mechanisms of viral diseases.