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Developmental Neuropathology
I was gratified by the most favorable reception and wide usage received by the first edition of this book. A decade seems to be a short period for a book on pathology, and yet it witnessed many important changes of concepts, along with a formidable growth of knowledge. The second edition required extensive reorganization. There are new chapters on mitochondriopathies, on peroxisomal diseases and on spongy myelino pathies. Major revisions and new additions were necessary in many chapters, for instance those on the dysplasias of the cerebral and of the cerebellar hemispheres, which were largely reorganized. The chapters on perinatal pathology were reordered and reorganized to give a more logic...
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Developmental Neuropathology of Schizophrenia
This volume reports the proceedings of a NATO Advanced Workshop held in Castelvecchio Pas coli, Italy, from August 28 - September 1, 1989. An important inspiration for this Workshop came from our studies in Helsinki and Denmark, which have found that exposure to an influenza epidemic during the second trimester of fetal development increases the risk of adult schizophrenia. This finding has stimulated an important new hypothesis in the study of the etiology of schizophrenia. It has suggested the possiblity that disturbances of brain development during gestation may contribute to the risk of adult schizophrenia. We determined that it would be of value to bring together schizophrenia researche...
Chemical Architecture of the Nervous System
Life, either as we think of it in the abstract in its highest sense, or life, as we think of it in terms of a compact living organism, is obviously the result of complex interaction of all of the components of the organism. One could therefore question the advisability of separating out the nervous system for a special detailed study in our age of overspecialization. The main purpose of the present Handbook is not to fragment further our approach or under standing of living phenomena, but, on the contrary, to try to summarize and integrate as much of the available information and thinking on the nervous system as is possible in a limited space. It is difficult to think of an area of modern b...
Developmental Neurobiology
In our attempts to interrogate Nature about the development of the nervous system, we ask such questions as "How do the nerve cells originate and how do the correct types of cells differentiate at their correct positions; how do the neurons link together to form circuits whose functions are properly coordinated; and how are the functions of nerve cells related to behavior, to thought, and to conscious ness?" Those problems are intellectually challenging, not only because solving them would give us practical advantages but also because while they remain unsolved they stimulate the imagination and challenge the intelligence. It is precisely because they are difficult and controversial and have...
International Review of Cytology
International Review of Cytology
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