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DNA Damage, DNA Repair and Disease
The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.
DNA Damage, DNA Repair and Disease Volume 1
The overall aim of this book is to give scientists in academia and industry a comprehensive overview of the field of DNA damage and DNA repair and related human diseases.
The Spirit of Wine
The Spirit of Wine invites readers to discover how the fruit of the vine can deepen one's spiritual life. Internationally acclaimed professor of comparative world religions Dr. Stephen Lloyd-Moffett reveals how a life filled with wine can act as a surrogate for traditional religions and spiritual communities. Whether you are a novice in the Church of Wine or already a devotee, this book will deepen your appreciation for wine by exploring the rich history of oenological conversions, mystical wine experiences, and ancient wine rituals. The book concludes with practical tips, including the secret to creating vibrant wine communities and the virtue of monastically-inspired spiritual drunkenness....
Friend of the Devil
High school can be hell. Literally. A demonic detective novel best devoured in a single sitting--from acclaimed TV writer Stephen Lloyd. Welcome to Danforth Putnam, boarding school for the elite, sprawled across its own private island off the coast of New England. Sam, a war vet who feels sure he’s seen it all, has been called here to find a stolen rare book. But as he corners D&D nerds, grills steroid-raging linemen, and interviews filthy-rich actresses, he soon senses that something far stranger—“witchy”, in fact—is afoot. When students start to meet mysterious and gruesome deaths, Sam realizes just how fast the clock is ticking. After joining forces with plucky, epilepsy-defying school reporter Harriet, Sam ventures into increasingly dark territory, unravelling a supernatural mystery that will upend everything he thinks he knows about this school—and then shatter his own reality. Toss Dracula into a blender, throw in a shot of hard-boiled detective fiction, splash in a couple drops of Stranger Things, and pour yourself a nice tall glass of Friend of the Devil.
Lloyd Register of Shipping 1921 Steamers
The Lloyd's Register of Shipping records the details of merchant vessels over 100 gross tonnes, which are self-propelled and sea-going, regardless of classification. Before the time, only those vessels classed by Lloyd's Register were listed. Vessels are listed alphabetically by their current name.
DNA Damage Recognition
Stands as the most comprehensive guide to the subject-covering every essential topic related to DNA damage identification and repair. Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular mechanisms employe
Progress in Nucleic Acid Research and Molecular Biology
Provides a forum for discussion of new discoveries, approaches, and idea in molecular biology. Contains contributions from leaders in their fields and abundant references. - Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology - Features contributions from leaders in their fields - Contains abundant references
Bleomycin: Chemical, Biochemical, and Biological Aspects
This book records the proceedings of a joint U.S.-Japan symposium on the chem istry, biochemistry, and biology of bleomycin, an antitumor antibiotic shown to be effective therapeutically against, eg, squamous cell carcinomas, Hodgkin's lymphoma, and testicular tumors. Several important and previously unreported observations were presented and the status of experimental work in the United States and Japan was reviewed; a summary and interpretation of the scientific presentations at the meeting has been prepared by the editor and is included as the first contribution in this volume. In addition to the symposium contributions, an experimental section has been included at the end of the book dea...
Enzyme Kinetics and Mechanism, Part F: Detection and Characterization of Enzyme Reaction Intermediates
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. - Spectroscopic Detection of Reaction Intermediates - Isotopic and Kenetic Detection of Reaction Intermediates - Chemical Trapping and Inhibitor Methods for Detecting Reaction Intermediates
