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This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.
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These 22 papers cover protein trafficking, lysosomal proteolysis, calpains, serpins, processing of cytoskeletal proteins, and complex proteolytic cascades of the circulatory system.
Freedom Of Communications. Final Report Of The Committee On Commerce, United States Senate. The Speeches Of Vice President Richard M. Nixon, Presidential Campaign Of 1960.
Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
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Biography of Thomas Francis Vinnicombe (1854-1932), originally from Pietermaritzburg, Natal, South Africa. Includes information about the Vinnicombe family, who immigrated to Port Natal in 1849 from London, England. Includes history of the Transvaal.