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The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.
"The purple book," gives you a comprehensive, up-to-date look at diagnostic imaging in an easy-to-read, bulleted format. Drs. Ralph Weissleder, Jack Wittenberg, Mukesh Harisinghani, and John W. Chen combine detailed illustrations and images with guidance on the latest applications of PET, CTA, and MRA into a portable resource for convenient reference wherever you go. Master the latest technologies, including hybrid PET, CTA, and MRA, through updated and expanded coverage of imaging modalities and their applications.
This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target validation to their use in clinical development programs. Chapters are devoted to the description of the drug discovery process, to the various imaging modalities preclinically and clinically, to applications of imaging during the optimization of a lead compound, addressing issues such as bioavailability and efficacy, and during drug safety evaluation.
First multi-year cumulation covers six years: 1965-70.
This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses.
Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements
This title includes a number of Open Access chapters.Considered the next industrial revolution, nanotechnology is an exciting field with new advances being reported regularly. It is a very diverse and highly interdisciplinary field, involving the science and engineering fields. Nanotechnolgy deals with the smallest building blocks of matter and inv
The book, Nanosensors for Futuristic Smart and Intelligent Healthcare Systems, presents a treatise on nanosensors technology including wearables, implantable devices and wireless tools. The recent pandemic (COVID-19) has changed the behaviour of people towards diagnosis of infectious diseases and monitoring remote patient health status in real-time. The main focus of this book is the basic concepts of nanomaterials and sensing paradigms for medical devices based on nanosensor technology. The book will be valuable to researchers, engineers and scientists interested in the field of healthcare for monitoring health status in real-time.
In 2020, areas of particular importance for technology trends will include biotechnology, nanotechnology, materials technology, and information technology. This report, the companion document to The Global Technology Revolution 2020, Executive Summary (Silberglitt et al., MG-475-NIC, 2006), assesses in detail a sample of 29 countries with respect to their ability to acquire and implement 16 key technology applications.
In 15 years MRI has evolved into an essential modality, developing from being a preferred neuroimaging method to becoming a whole-body, comprehensive imaging approach. For this, various coils, pulse sequences, and contrast media have been developed. The complexity of the factors to consider often represents an obstacle not only to beginners but also to more experienced technicians and physicians. Since routine diagnostic questions represent more than 90% of clinical examinations, the intention of the editors and authors was to provide an understandable book for this purpose. The book gives practical information about performing effective and efficient MR examinations in daily practice. Solving clinical questions with new sequences should no longer be difficult for beginners in the field.