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Of Blood and Spells
Magic is born of the darkest of spells... Dive into this collection of paranormal stories, where three witches defy the laws of time and learn that dark magic isn’t always as it seems—from a headstrong witch who falls through time to Cuba in 1898, to a cursed witch who is forced to work alonside an enemy vampire, to a demon assassin who falls in love with her target. This three-series collection will take you on an adventure filled with dark magic, time travel, and enchanting romance that spans lifetimes. This collection includes: Timecaster Chronicles Twisted by Time Devoured by Darkness Bound by Blood Nightcaster Chronicles The Cursed Witch The Fallen Demon The Lost Phoenix Bloodcaster Chronicles The Demon's Kiss The Angel's Vow The Reaper's Call
Comprehensive Medicinal Chemistry II
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organis...
Meeting the Needs of Older Adults with Serious Illness
Meeting the Needs of Older Adults with Serious Illness: Challenges and Opportunities in the Age of Health Care Reform provides an introduction to the principles of palliative care; describes current models of delivering palliative care across care settings, and examines opportunities in the setting of healthcare policy reform for palliative care to improve outcomes for patients, families and healthcare institutions. The United States is currently facing a crisis in health care marked by unsustainable spending and quality that is poor relative to international benchmarks. Yet this is also a critical time of opportunity. Because of its focus on quality of care, the Affordable Care Act is poise...
River Culture
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Cancer Genomics
The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
Novel Biomarkers in the Continuum of Breast Cancer
This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer. The volume covers topics related to breast cancer risk and prevention, prediction of response to today’s standard therapies, and markers capable of influencing treatment decisions in the near future. Chapter authors combine their wide-ranging expertise to review the current status of the biomarker and to offer their individual perspectives on how biomarkers may be used in future treatments and research. Breast cancer continues to be the most common malignancy diagnosed in women in the Western world. While there are multiple treatment approaches for breast cancer, today more than ever we recognize that each tumor is unique. The challenge ahead is to consider how to best use validated and novel biomarkers to select the most appropriate treatment(s) for individual patients.
Blaustein's Pathology of the Female Genital Tract
This is the third edition of the widely acclaimed Blaustein's Pathology of the Female Genital Tract. The fully illustrated work is an authoritative, comprehensive, and up-to-date textbook and standard reference source in gynecologic and obstetric pathology. It is aimed at practicing pathologists, obstetricians and gynecologists, and residents in these specialties. The book emphasizes the correlation between clinical and pathologic features of female genital tract disease by examining the pathophysiology of individual organ systems. New adjunctive techniques such as immunohistochemistry and molecular DNA analysis are introduced when useful, for example, in the study of premalignant and malign...
