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Cloning
Cloning was first published in 1985. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions. Cloning has become in recent years a subject of widespread speculation: the word is a source of fear and wonder, the concept a jumping-off point for the fantasies of cartoonists, film producers, and novelists. With this book, cell biologist Robert Gilmore McKinnell provides the first clear scientific explanation of the procedure for general readers. Cloning is best defined as the asexual reproduction of genetic duplicates. The word clone derives from the Greek word fo...
Cloning
Cloning was first published in 1985. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions. In this, the first published monograph devoted exclusively to the cloning procedure, Professor McKinnel reviews the results obtained in nuclear transplantation experiments with amphibia and provides an extensive discussion of the methodology used. He explains that while biologists generally use the word "cloning" to refer to the production of multiple genetically identical individuals, he uses it in a more general sense to refer to one or more individuals produced by ...
Peril in the Ponds
When deformed frogs-many with missing legs or eyes, footless stumps, or misshapen jaws-began to emerge from Minnesota wetlands, alarm bells went off. What caused such deformities? Pollution? Ultraviolet rays? Biological agents? And could the mysterious cause also pose a threat to humans? Former government biologist Judy Helgen provides an inside view of a highly charged environmental issue that continues to spark controversy among scientists, politicians, and government agencies. Book jacket.
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The Understanding, Prevention and Control of Human Cancer
The Understanding, Prevention and Control of Human Cancer is an account of how a married couple opened understanding of environmental carcinogenesis. Elizabeth Cavert and James A. Miller showed that enzymes of the human body activate and enable otherwise benign organic chemicals to combine with DNA in such a manner that cancer results. Their work is of particular note because cancer causes more loss of life-years than the sum of all other causes of death—and, as the President’s (USA) Cancer Panel warned, environmental carcinogenesis is a form of cancer that has been previously “grossly underestimated”. The Millers’ cancer research led to tests that identify dangerous chemicals which in turn permits prevention and thus the control of human cancer.
The Biological Basis of Cancer
This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.
The Pathobiology of Neoplasia
This book is directed primarily to advanced graduate and medical students, postdoctoral trainees, and established investigators having basic research interests in neoplasia. Its content is based in part on the lecture outlines and selected histopathology laboratory components of an advanced course entitled The Pathobiology of Experimental Animal and Human Neoplasia, developed by me for the Experimental Pathology Curriculum of the Department of Pathology at the Medical College of Virginia. In this regard, an effort has been made to integrate pathology with carcinogenesis, genetics, biochemistry, and cellular and molecular biology in order to present a comprehensive and current view of the neo...
