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The isolation of leptin in 1994 and its characterization as a factor influencing appetite, energy balance, and adiposity, immediately thrust the polypeptide into the rapidly growing body of literature centered on the physiology of obesity. The growing clinical awareness of obesity as a major health risk in developed societies dovetailed perfectly with any of a number of roles that leptin might play in this abenant physiological condition. Almost unnoticed amidst the excitement generated by early leptin publications was the suggestion that the "fat hormone" might also regulate a wide range of systems and events important to reproduction, including pubertal development, gonadal endocrinology, ...
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Examines the body's largest organ, including its qualities, the history of its conditions and diseases, and the impact of its color and irregularity.
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This lively and far-reaching account of the politics, religion, and culture of England in the century and a half after the Norman Conquest provides a vivid picture of everyday existence, and increases our understanding of all aspects of medieval society. This was a period in which the ruling dynasty and military aristocracy were deeply enmeshed with the politics and culture of France. Professor Bartlett describes their conflicts, and their preoccupations - the sense of honour, the role of violence, and the glitter of tournament, heraldry, and Arthurian romance. He explores the mechanics of government; assesses the role of the Church at a time of radical developments in religious life and organization; and investigates the peasant economy, the foundation of this society, and the growing urban and commercial activity. There are colourful details of the everyday life of ordinary men and women, with their views on the past, on sexuality, on animals, on death, the undead, and the occult. The result is a fascinating and comprehensive portrayal of a period which begins with conquest and ends in assimilation.