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Biochemistry and Molecular Biology Compendium
While biomedical investigation has greatly advanced, investigators have lost touch with and inadvertently corrupted significant nomenclature at the foundation of their science. Nowadays, one has to be an insider to even understand the titles of journals, as modern biochemists have a tendency to invent new terms to describe old phenomena and apply a
CHEMICAL REAGENTS FOR PROTEIN MODIFICATION
The chemical modification of proteins; Amino acid analysis; Peptide separation by reverse-phase high performance liquid chromatography; Methods for sequence determination; Chemical cleavage of peptide bonds; The modification of cystine; The Modification of cystine - cleavage of disulfide bonds; The modification of methionine; Modification of histidine residues; The modification of Lysine.
Handbook of Biochemistry and Molecular Biology
A comprehensive compendium of basic biochemical information, the convenient easy-to-use format of this revised edition includes physical and chemical data on proteins, lipids, vitamins, nucleic acids and carbohydrates. New sections will be added on DNA modification, novel protein analysis methods, lipidomics and chemical biology.
Development and Application of Biomarkers
First introduced to biomedical research in 1980, the term biomarker has taken on a life of its own in recent years and has come to mean a number of things. A comprehensive assessment of biomarkers, this book covers the history and current status of the application of biomarkers in diagnostics and prognostics. It explores the technology used for the study of biomarkers, and the validation of biomarkers including a comparison of the various technologies used to identify and measure biomarkers. The editors emphasize the technology underlying biomarkers and the translation of basic science to clinical laboratory technology, including the commercial development of biomarkers. The book also covers proteomics and proteomic technologies and their applications in the identification of biomarkers.
The Chemical Biology of Thrombin
Chemical Biology of Thrombin is a comprehensive review of thrombin as regulatory protease, perhaps one of the most important enzymes in hemostasis. It focuses on work from 1970's to the present time. Thrombin has some emerging therapeutic uses such the treatment of pseudoaneurysms and an important role in the extravascular space.
Chemical Modification of Biological Polymers
Examining the chemical modification of biological polymers and the emerging applications of this technology, Chemical Modification of Biological Polymers reflects the change in emphasis in this subsection of biotechnology from the study of protein structure and function toward applications in therapeutics and diagnostics. HighlightsThe basic organi
Biotechnology of Plasma Proteins
The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to
Application of Solution Protein Chemistry to Biotechnology
Reflecting the versatility of the author's science and the depth of his experience, Application of Solution Protein Chemistry to Biotechnology explores key contributions that protein scientists can make in the development of products that are both important and commercially viable, and provides them with tools and information required for successfu
Approaches to the Conformational Analysis of Biopharmaceuticals
The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches to analysis exists, finding the most viable ones wou
Techniques in Protein Modification
This exciting laboratory support book encompasses the encyclopedic coverage of the most frequently used methods for the site-specific chemical modification of proteins. In a concise manner, it presents methods for the characterization of modified proteins, including: amino acid analysis protein sequence analysis chemical cleavage of protein chains chromatographic separation of peptides It also discusses various approaches to the determination of solution protein concentration. It includes a complete literature survey of the various reagents, a list of the most commonly used reagents with their physical and chemical properties, and a list of preferred reagent suppliers.
