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Principles of Cloning
Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning techni...
Genome Editing in Neurosciences
This book is open access under a CC BY 4.0 license. CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease. This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.
Animal Virus Genetics
Animal Virus Genetics is a collection of scientific presentations of the ICN-UCLA Symposia on Molecular and Cellular Biology, held at the University of California, Los Angeles in 1980. The papers in the compendium focus on the basic genetic model systems; the uses of genetic approaches to study basic problems in molecular biology; and on the increasing application of genetic systems to the study of more complex viral-host interactions such as viral virulence and persistence. Microbiologists, cellular biologists, and virologists will find the book insightful.
Genome Editing in Neurosciences
This book is open access under a CC BY 4.0 license. CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease. This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.
Tumorviruses, Neoplastic Transformation and Differentiation
If tumor viruses did not exist in nature they might have been created by scientists interested in basic mechanisms of develop ment, differentiation, and tumorigenesis. In contemporary euka ryotic cell biology tumor viruses playa similar role to that which bacteriophages once had for the molecular biology of prokary otes. Tumor viruses provide extremely useful probes for the above cellular processes since their life cycle is genetically pro grammed and can be followed at DNA, RNA, and protein levels. The experimental systems reviewed in this volume utilize a wide variety of viruses. A comprehensive introduction to this field has recently been published in the volumes of Molecular Biol...
The Biology of Complex Organisms
On December 6, 1961, a contract was signed by which the research institute of the Wander AG in Freiburg became the Max-Planck-Institut fUr Immunbiologie. The transfer of ownership took place during a happy expansion phase of the Max-Planck Society in which a growing economy in Germany allowed the foundation of many new research institutes by the Max-Planck-Society and other organizations. Nevertheless, it was a remarkable event. The acquisition by an academic organization of an institute formerly operated by an industrial company was rather unusual, not to speak ofthe fact that not only the facilities but also the entire scientific personnel were taken over. Retrospectively, the 40 years of ...
Harvey Lectures
The Harvey Society was founded in 1905 by thirteen New York City scientists and physicians with the purpose of forging a closer relationship between the purely practical side of medicine and the results of laboratory investigation. The Harvey Society Lectures reflect the evolution of physiology and physiological chemistry into biochemistry and the development of molecular biology from the roots of bacteriology and biochemistry in this century.
Stem Cells, Human Embryos and Ethics
Is it acceptable from an ethical point of view to use stem cells from human embryos for scientific research and clinical therapy? And what are the weaknesses and strengths of various opinions and positions when they are critically evaluated? These are the main problems dealt with in this book. The various chapters as a whole give a comprehensive, many-sided and balanced discussion of the subject. The book contains contributions from biological, medical, social, political, philosophical and theological perspectives. The authors have been chosen because of their professional competence, many of them being respected scholars on a top international level. They give an updated contribution from t...
Genetic Engineering
The ability to alter the genetic code is one of the most powerful aspects of modern science. With genetic engineering, scientists can make a mouse's muscles bigger, create animals that are virtually identical to one another, and cause mosquitoes to pass fatal genes to their offspring, halting the spread of disease-causing organisms. Advances in gene editing, the ability to directly manipulate DNA, have placed even greater power in researchers' hands and renewed ethical concerns surrounding the implementation of genetic engineering. This comprehensive volume explores these topics, describes the methods by which scientists produce genetically modified organisms (GMOs), and highlights ethical issues associated with GMOs.
