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This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.
Contemporary Latin America presents the epochal political, economic, social, and cultural changes in Latin America over the last 40 years and comprehensively examines their impact on life in the region, and beyond. Provides a fresh approach and a new interpretation of the seismic changes of the last 40 years in Latin America Introduces major themes from a humanistic and universal perspective, putting each subject in a context that readers can understand and relate to Focuses on ‘Ibero-America'--Brazil and the eighteen countries that were formerly Spanish possessions- while offering valuable comparative views of the non-Iberian areas of the Caribbean Emphasizes the global, regional and national dimensions of the region's recent past
Designated 'Molecule of the Year' in 1992 in recognition of its many biological roles, nitric oxide has wide significance in the world around us and the story of nitric oxide is still unfolding. This small and seemingly innocent molecule has for many years been known to play a significant role in both the creation of photochemical smogs and in the nitrogen cycle. It has an interesting chemistry as a metal ligand, and the bonding within the nitric oxide molecule has been extensively studied. More recently, the molecule has been in the spotlight for the role it plays in controlling blood flow, in the immune system and in brain activity. Life, Death and Nitric Oxide covers many of the topics relating to nitric oxide, from smog and catalytic converters to tumour growth, blood flow and Viagra, with the aim of finding out why such a simple molecule can do so much.
First multi-year cumulation covers six years: 1965-70.
Reproducibility is fundamental to the scientific method. After reading a paper describing research findings, a scientist should be able to repeat the experiment and obtain the same results. Yet an alarming number—perhaps as high as 90 percent—of published biomedical research papers face challenges in independent replication. Such issues range from honest mistakes to outright fraud. The scope of this crisis, however, underscores deeper systemic issues within the scientific community: its culture, incentives, and institutions. In Unreliable, the distinguished scientist Csaba Szabo examines the causes and consequences of the reproducibility crisis in biomedical research, showing why the fac...
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In Pura vida (Life is good)Spanish is more than vocabulary and grammar, just as Spanish-speaking cultures are more than products and practices. In this learner-centered introductory program, the authors’ commitment to a methodology based on true-to-life experiences brings Spanish to life. Pura vida is the discovery of a Spanish-speaking world through the experiences of real people who share anecdotes and reflections on those experiences. Students relate to these people and make deeper, more meaningful connections between language and culture, and acquire Spanish with an unparalleled sense of personal engagement. In this 12-chapter introductory program, students don’t only learn Spanish for real life, but also from real life. They discover that there is not just one homogeneous Hispanic culture, but rather that each Spanish-speaking country has its own rich, unique culture and that the people who live in these countries speak one common language with different accents, characteristics, and idiosyncrasies. The program offers truly seamless integration of cultural notions and language instruction and features 100% contextualized and personalized activities.
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