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Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtu...
This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.
Functional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divid...
Second edition of a text first published in 1981 for geography students at upper secondary level. Uses case studies, questions, practical exercises and a range of data presentation techniques to promote an understanding of location, distribution and interaction of rural and urban settlements. New to this edition are 1993 statistics, new case studies, contemporary issues, use of models and an additional chapter of assessment exercises featuring colour topographic maps. Includes an index.
Renowned biochemist, Dr Libby reveals the science of weight loss, made simple. Discover how your body really works and find the tools you need to win the battle of the bulge and to keep your weight off - for good. Discover what your body needs to achieve permanent weight loss. Confused about what's more effective - a high carb or high protein diet? Are you eating all the right foods and exercising yet still not losing weight? Do you do your best with food and movement yet feel like your body has a mind of its own and seems to betray you? Do you eat emotionally and wish you could change this? Or perhaps you feel and look your best, and simply want to learn more about how your fat burning syst...
In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.