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Frontiers in Computational Chemistry presents contemporary research on molecular modeling techniques used in drug discovery and the drug development process: computer aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. The sixth volume of this series features these six different perspectives on the application of computational chemistry in rational drug design: 1. Computer-aided molecular design in computational chemistry 2. The role of ensemble conformational sampling using molecular docking & dynamics in drug discovery 3. Molecular dynamics applied to discover antiviral agents 4. Pharmacophore modeling approach in drug discovery against the tropical infectious disease malaria 5. Advances in computational network pharmacology for Traditional Chinese Medicine (TCM) research 6. Progress in electronic-structure based computational methods: from small molecules to large molecular systems of biological significance
This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members of the International Taurine Society, including COVID-19, cancer, heart disease, and diabetes, among others. Chapters are written by Taurine experts across the globe in North and South America, Asia, and Europe. A majority of the articles are based on original studies recently carried out in individual laboratories worldwide. The book is divided into eight parts, each covering a unique aspect of Taurine. Each section will highlight new research findings on Taurine and its application in various human systems, including the nervous system, immune system, and cardiovascular system, to combat disease. The first section covers COVID-19, the dominant health event of 2020. Experts will explore and clarify the potential therapeutic effectiveness of Taurine against COVID-19. The volume will promote further research into the application of Taurine in human health, and will be of use to a wide audience, including basic and clinical scientists, pharmaceutical and nutraceutical companies, and libraries.
Temos o prazer de lançar o primeiro livro internacional do ano de 2022 voltado a área do desenvolvimento, que tem como título Principles and concepts for development in nowadays society, essa obra contém 152 artigos voltados a área multidisciplinar, sendo a mesma pela Seven Publicações Ltda. A Seven Editora, agradece e enaltasse os autores que fizeram parte desse livro. Desejamos uma boa leitura a todos
Paper-Based Analytical Devices for Chemical Analysis and Diagnostics is a valuable source of information for those interested in microfluidics, bioanalytical devices, chemical instrumentation/mechanization, in-field analysis, and more. This book provides a critical review of the scientific and technological progress of paper-based devices, as well as future trends in the field of portable paper-based sensors for chemical analysis and diagnostics directly at point of need. It uniquely focuses on the analytical techniques associated with each type of device, providing a practical framework for any researcher to use while learning how to use new types of devices in their work, deciding which ones are best for their needs, developing new devices, or working toward commercialization. - Reviews the evolution of this area and offers predictions for the future of the field of paper-based analytical devices - Explores the analytical techniques used in development of paper-based devices - Discusses challenges and shortcomings specific to each type of device, helping users and developers to avoid pitfalls
The two-volume set LNAI 13073 and 13074 constitutes the proceedings of the 10th Brazilian Conference on Intelligent Systems, BRACIS 2021, held in São Paolo, Brazil, in November-December 2021. The total of 77 papers presented in these two volumes was carefully reviewed and selected from 192 submissions.The contributions are organized in the following topical sections: Part I: Agent and Multi-Agent Systems, Planning and Reinforcement Learning; Evolutionary Computation, Metaheuristics, Constrains and Search, Combinatorial and Numerical Optimization, Knowledge Representation, Logic and Fuzzy Systems; Machine Learning and Data Mining. Part II: Multidisciplinary Artificial and Computational Intelligence and Applications; Neural Networks, Deep Learning and Computer Vision; Text Mining and Natural Language Processing. Due to the COVID-2019 pandemic, BRACIS 2021 was held as a virtual event.
Rodrigo Barneschi simplesmente não concebe o futebol sem a presença do torcedor visitante. Para ele, frequentador assíduo das arquibancadas, tanto o abnegado que viaja para seguir o clube do coração como o fanático que cruza a própria cidade para ficar rouco em um setor isolado do estádio rival são protagonistas de um espetáculo que, despojado do forasteiro, perde grande parte de seu sentido. Em sua estreia como escritor, o autor nos guia por diferentes estádios do Brasil e da América do Sul, em uma cruzada por campos decadentes, fartos de obstáculos e transtornos aos visitantes que tentam acompanhar seus times nos jogos fora de casa. Com um relato que mistura crônica, diário de viagens e jornalismo -- e permeado por forte crítica social --, Barneschi reivindica em "Forasteiros" o direito ao torcer. Dele e de qualquer torcedor disposto a ir ao estádio do adversário para encarar sua missão: a de assumir o protagonismo de um espaço que lhe pertence.