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Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, summarizes the most important developments in in vitro models for predicting the permeability of drugs. This book is structured around three different approaches, summarizing the most recent achievements regarding models comprising (i) immortalized cells with an intrinsic ability to grow as monolayers when seeded in permeable supports, (ii) primary cells isolated from living organisms and directly cultured as barrier monolayers, and (iii) tissue-based models constructed with cell lines and extracellular matrix that resembles the tridimensional structure of mucosae and other biolo...
"The one source that sets reference collections on Latin American studies apart from all other geographic areas of the world.... The Handbook has provided scholars interested in Latin America with a bibliographical source of a quality unavailable to scholars in most other branches of area studies." —Latin American Research Review Beginning with volume 41 (1979), the University of Texas Press became the publisher of the Handbook of Latin American Studies, the most comprehensive annual bibliography in the field. Compiled by the Hispanic Division of the Library of Congress and annotated by a corps of more than 130 specialists in various disciplines, the Handbook alternates from year to year b...
Rarely visited by outsiders, the ranchers of the Sierra de la Giganta in Baja California Sur live much as their ancestors have for the past two centuries. They raise goats and cattle and grow a magnificent variety of fruits, vegetables, and flowers. In this book a gifted photojournalist introduces us to individual ranchers and their families and describes their traditional practices and the ways they have adapted to twenty-first-century challenges and technological advances. Marchand’s photographs and text are both informative and intimate. His introduction to this little-known corner of Mexico will delight travelers and scholars alike.
Beginning with volume 41 (1979), the University of Texas Press became the publisher of the Handbook of Latin American Studies, the most comprehensive annual bibliography in the field. Compiled by the Hispanic Division of the Library of Congress and annotated by a corps of more than 130 specialists in various disciplines, the Handbook alternates from year to year between social sciences and humanities. The Handbook annotates works on Mexico, Central America, the Caribbean and the Guianas, Spanish South America, and Brazil, as well as materials covering Latin America as a whole. Most of the subsections are preceded by introductory essays that serve as biannual evaluations of the literature and...
Although Villavicencio, the capital of the Department of Meta, is located just 120 miles from Bogot , the mountains of the eastern Andean Cordillera lies between the two cities. As a result, after its founding in 1842, Villavicencio remained an isolated frontier outpost for more than one hundred years--even though "El Portal de la Llanura" ("the Gateway to the Plains") provided the principal access to Colombia's tropical plains (Llanos), a vast grassy region cut by tributaries connecting with the Meta and Guaviare rivers and eventually the Orinoco. Nineteenth- and twentieth-century governments in Bogot regarded the Llanos as the "Eastern Lands of Promise," underestimating the geographic and ...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.