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The Role of Chromenes in Drug Discovery and Development
Chromene is a naturally abundant heterocyclic compound found in alkaloids, tocopherols, terpenes and other compounds. Its derivatives can be used as a scaffold that exhibits pharmacological activity in the human body. Chromene drugs and related bioactive molecules are the prime focus of this reference. It presents 13 thoroughly researched chapters that comprehensively cover all aspects about the molecule. Starting with a detailed introduction to its role and importance in drug discovery, the book goes into the details of chromene structure, synthesis and pharmacology. Readers can gain knowledge of different commercial medicines based on chromene and its pharmacological activity against diffe...
Emerging Modalities in Mitigation of Antimicrobial Resistance
Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.
Plants as Medicine and Aromatics
Plant‐based medicines and aromatics are increasingly in demand in the healthcare sector all over the globe where they are used, not only for the treatment of various diseases, but also for maintaining good human health. Plants as Medicine and Aromatics: Uses of Botanicals reviews modern uses of ancient botanicals as medicine and aromatics, including chapters on both traditional usage and modern drug discovery development, as well as clinical research and development in ancient medicinal herbs. Features: Assesses the status of aromatics and medicinal plants as well as their modern uses. Elucidates the uses of plants within traditional culture practices for the prevention and treatment of diseases. Examines contemporary approaches being used to explore medicinal botany. A volume in the Exploring Medicinal Plants series, Plants as Medicine and Aromatics: Uses of Botanicals presents a comprehensive understanding in terms of modern uses of botanicals of medicinal and aromatic plants. It is useful to researchers, teachers, cultivators, students, and for those interested in herbal medicine.
Natural Scaffolds for Prevention and Treatment of Neurodegenerative Disorders
Neurodegenerative diseases affect millions of people worldwide and are a group of several diseases with distinct pathology, physiology, prevention, and treatment strategies. Recently, natural products especially derived from medicinal plants are gaining momentum to manage neurodegenerative disease safely and effectively. Therefore, there is an urgent need to provide a ready roadmap for scientifically validated value-added nutraceutical and pharmaceutical safe and effective product for the management of various neurodegenerative diseases Natural Scaffolds for Prevention and Treatment of Neurodegenerative Disorders will provide compiled information stating several identified neurodegenerative ...
Medicinal Plants for the Management of Neurodegenerative Diseases
Ageing is the main reason for most neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). About 10% of individuals aged ≥65 years develop AD, which continuously increases with growing age. Medicinal plants have been used for age-related neurodegenerative disorders for a long time. These plants are rich in terms of various phytochemical constituents such as flavonoids, sterols, alkaloids, saponins, and terpenoids. Different scientific studies have been carried out on these medicinal herbs, e.g., anti-inflammatory, antioxidant, and neuro-regenerative activities that may be used in the treatment of AD and other age-related diseases. These medicinal pl...
Therapeutic Medicinal Plants in Traditional Persian Medicine
Traditional Persian Medicine (TPM) is one of the oldest medical doctrines, globally known due to pioneering physicians and scientists. The greatest source of natural medicines in TPM originates from medicinal plants. Therapeutic Medicinal Plants in Traditional Persian Medicine provides a background on the history of TPM, as well as an introduction to 40 of the most popular medicinal plants used in TPM. It is a practical guide for readers interested in medicinal plants used in the prevention, management, and treatment of different diseases. Features: Includes both traditional therapeutic applications and modern evidence/ uses Makes a comparison between preclinical and clinical studies Provides information on major chemical constituents, therapeutic uses, adverse reactions, and safety for each plant species A volume in the “Exploring Medicinal Plants” series, this book is a valuable resource for researchers, students, academicians, and scientists dealing witth medicinal plants, as well as for those interested in the fields of pharmacognosy, naturopathy, phytotherapy, and traditional medicines.
Natural Bioactives from the Endophytes of Medicinal Plants
Endophytes from medicinal plants have garnered global attention due to their remarkable capacity to produce unique phytochemicals, pharmaceuticals and promising lead compounds. This book explores cutting-edge advancements in endophytic fungi research, encompassing a comprehensive exploration of their biodiversity, ecological dynamics, mechanisms of interaction and adaptive strategies. The book offers valuable insights into the therapeutic potential, agricultural applications, environmental impacts and commercial prospects of these fascinating organisms. While the contemporary books are limited to either taxonomic, ecological or practical discussions, this book presents a systematic compilati...
Green Chemistry for Environmental Remediation
The book explains the importance of chemistry in solving environmental issues by highlighting the role green chemistry plays in making the environment clean and green by covering a wide array of topics ranging from sustainable development, microwave chemical reaction, renewable feedstocks, microbial bioremediation, and other topics that, when implemented, will advance environmental improvement. Green Chemistry for Environmental Remediation provides insight on how educators from around the world have incorporated green chemistry into their classrooms and how the principles of green chemistry can be integrated into the curriculum. The volume presents high-quality research papers as well as in-...
Exploring Medicinal Orchids
Orchids are fascinating ornamental flowers with a huge market both as cut flowers and potted plants, but they are also used in the traditional medicine system as they can be rich in phytochemicals with exceptional medicinal properties. This book, Exploring Medicinal Orchids, is a comprehensive guide for medicinally important orchids, their diversity, and their use in traditional and folk medicines. It presents information on secondary metabolites of medicinally active orchid species, pharmaceutical and medicinal applications, and describes advanced techniques of biotechnology in the conservation of medicinal orchids. Features Dedicated chapters discuss phytochemical constituents and medicina...
