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Genome-wide Association Study of 40,000 Individuals Identifies Two Novel Loci Associated with Bipolar Disorder
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe oscillations of mood and behavior. Genome-wide association studies (GWAS) have identified several risk loci that together account for a small portion of the heritability. To identify additional risk loci, we performed a two-stage meta-analysis of >9 million genetic variants in 9,784 bipolar disorder patients and 30,471 controls, the largest GWAS of BD to date. In this study, to increase power we used ~2,000 lithium-treated cases with a long-term diagnosis of BD from the Consortium on Lithium Genetics, excess controls, and analytic methods optimized for markers on the Xchromosome. In addition to four known l...
The Holistic Rx for Kids
Holistic, functional, integrative medicine meets the parenting world! Board-certified holistic family physician and author of The Holistic Rx Madiha M. Saeed, MD shifts the focus from adults to children in her timely new book. The Holistic Rx for Kids offers holistic parenting guidelines for raising the whole child—healthy brain, body and soul—in a changing world. As chronic physical and mental health conditions and destructive behaviors are on the rise, we need to shift the way we parent our children to address these concerns. Based on the latest science, Dr. Saeed uncovers how our children’s brains, bodies, and behaviors are being hijacked and presents real-life, actionable steps par...
Historical Discourse
Reprint of the original, first published in 1867.
New York Supplement
Includes decisions of the Supreme Court and various intermediate and lower courts of record; May/Aug. 1888-Sept../Dec. 1895, Superior Court of New York City; Mar./Apr. 1926-Dec. 1937/Jan. 1938, Court of Appeals.
The Bergen Family
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