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Studies in Natural Products Chemistry
This volume presents frontier reviews of recent developments in bioactive natural products in cutting-edge areas by eminent experts in their respective fields. It is an essential addition to this important series on Natural Products Chemistry, generally acknowledged to be the leading series on this topic.• The first seven reviews cover recent developments in the field of bioactive marine natural products.• Additional coverage includes Novel Domino reactions; medicinal plants and phytochemicals; recent developments in bioactive natural peptides; the chemistry and pharmacology of natural cyclic lipopeptides; and the biological activities of Salvia .• The text includes a comprehensive review of biologically active compounds of semi-metals such as boron, silicon, arsenic, selenium and tellurium.
Macrolide Antibiotics
Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.
Ivermectin
Specialists have placed ivermectin on the drug podium, along with penicillin and aspirin. Its discoverers and developers received a Nobel Prize in Medicine in 2015, and until 2020 there seemed to be a worldwide consensus about the benefits of this naturally-occurring component. More than 300 million people from the world's poorest countries take ivermectin annually, either as a treatment or as a prophylaxis. The outbreak of Covid-19 put ivermectin in the headlines all over the world. Thousands of doctors in different countries claim that its use (sometimes combined with vitamins and other drugs) is an effective early treatment against the coronavirus and dozens of clinical trials carried out support this position. What would happen if we found that Ivermectin is an effective treatment or preventive method against Covid-19 and that it was rejected to favor the massive vaccination?
Tore Godal and the Evolution of Global Health
This book is an interconnected history of the evolution of global health in the decades before 2019, told through the prism of six decisive moments in which individuals from the World Health Organization (WHO), philanthropic foundations, academia and bilateral agencies came together to shape the world. These critical junctures are accessed via the life and work of Norwegian immunologist Tore Godal, one of the most influential health physicians of all time. Godal’s career over the past 50 years offers a window into the profound events that have shaped the health and well-being of millions across the globe, including the first free donation of a drug for the treatment of river blindness; the...
The Power of Plagues
The Power of Plagues presents a rogues' gallery of epidemic- causing microorganisms placed in the context of world history. Author Irwin W. Sherman introduces the microbes that caused these epidemics and the people who sought (and still seek) to understand how diseases and epidemics are managed. What makes this book especially fascinating are the many threads that Sherman weaves together as he explains how plagues past and present have shaped the outcome of wars and altered the course of medicine, religion, education, feudalism, and science. Cholera gave birth to the field of epidemiology. The bubonic plague epidemic that began in 1346 led to the formation of universities in cities far from ...
Chemical, Biological and Environmental Engineering - Proceedings of the International Conference on Cbee 2009
Held in Singapore from 9 to 11 October 2009, the 2009 International Conference on Chemical, Biological and Environmental Engineering (CBEE 2009) aims to provide a platform for researchers, engineers, academicians as well as industrial professionals from all over the world to present their research and development activities in chemical, biological and environmental engineering. Conference delegates will also have the opportunity to exchange new ideas and application experiences, establish business or research relations and find global partners for future collaboration. Sample Chapter(s). Chapter 1: The Future of Biopharmaceutics'' Production (92 KB). Contents: Study on Pyrolysis Characterist...
Natural Product Biosynthesis
Authored by leading experts in the enzymology of natural product biosynthesis, this textbook provides a thorough description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Although some 500-600,000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism. This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, to pharmacognocists and chemical ecologists, to bioengineers and synthetic biologists.
The Search for Bioactive Compounds from Microorganisms
Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.
Pharmacology and Pharmacotherapeutics
The 25th revised edition of Pharmacology and Pharmacotherapeutics continues to maintain its status as an up-to-date, accurate and reliable text for medical students as well as practicing physicians. The advances in molecular biology have significantly influenced the understanding of pathogenesis of diseases and development of newer drugs. The real challenge, however, remains in application of the available information while treating a patient. This book has always placed before the readers an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. The current edition balances the ...
Recent Advances in Biotechnology
In last decades rapid scientific and engineering developments have been occuring within the context of Biotechnology. If the World Economy is to benefit fully from the advances in biosciences and biochemical engineering, it must be able to focus new knowledge on commercially appropriate targets. Modern Biotechnology is a mixture of far reaching innovation superimposed on an industrial background and it represents a means of production with bright prospects, challenging problems and stimulating competition. This NATO Advanced Study Institute on "RECENT ADVANCES IN INDUSTRIAL APPLICATIONS OF BIOTECHNOLOGY" held between September 16-27, 1991 in Ku§Etdasl was the first ASI on Biotechnology :Ln ...
