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In this book we have experts writing on various neuroscience topics ranging from mental illness, syndromes, compulsive disorders, brain cancer and advances in therapies and imaging techniques. Although diverse, the topics provide an overview of an array of diseases and their underlying causes, as well as advances in the treatment of these ailments. This book includes three chapters dedicated to neurodegenerative diseases, undoubtedly a group of diseases of huge socio-economic importance due to the number of people currently suffering from this type of disease but also the prediction of a huge increase in the number of people becoming afflicted. The book also includes a chapter on the molecular and cellular aspects of brain cancer, a disease which is still amongst the least treatable of cancers.
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En el desarrollo de la democracia inevitablemente surgen dilemas constitucionales acerca de quién debe tener la última palabra institucional en el proceso político de toma de decisiones, y de acuerdo con qué criterios. Dentro de estos dilemas entra en juego el lugar que deben ocupar los jueces en las estructuras de decisión política desde la justicia constitucional. El libro representa, pues, un ensayo que intenta abordar el problema de la autoridad final en una democracia, y para ello navega entre los diversos dilemas morales, normativos e institucionales que presenta el control judicial de las leyes en las democracias modernas. En este sentido, el libro nos alerta de los peligros de ...
This volume will serve as a guide for students in the field of neurobiology, and be a bridge between basic science researchers, doctors, and surgeons in clinical practice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Neurobiology: Methods and Protocols aims to ensure successful results in the further study of this vital field.
This volume explores scientific methodologies currently employed to integrate observational developmental biology, tissue explant and cell-based approaches and genetic/molecular technologies to develop a holistic understanding of craniofacial development. Chapters guide readers through the use of disparate models to study formation of the head and face (c. elegans, zebrafish, mouse, alongside human imaging approaches), together with cell culture, tissue explant and in vivo cell imaging and analysis techniques. At the molecular level, chapters include analysing gene expression using in-situ hybridisation and single-cell RNA-Sequencing (scRNA-SEQ), as well as genetic modification techniques su...
This volume explores scientific methodologies currently employed to integrate observational developmental biology, tissue explant and cell-based approaches and genetic/molecular technologies to develop a holistic understanding of craniofacial development. Chapters guide readers through the use of disparate models to study formation of the head and face (c. elegans, zebrafish, mouse, alongside human imaging approaches), together with cell culture, tissue explant and in vivo cell imaging and analysis techniques. At the molecular level, chapters include analysing gene expression using in-situ hybridisation and single-cell RNA-Sequencing (scRNA-SEQ), as well as genetic modification techniques su...
Christine M. Korsgaard has had a profound influence on moral philosophy over the past forty years. This volume is written in her honor, engaging with seminal questions that recur in her writing and teaching and staking out provocative new positions on topics in ethics, agency, and the normative dimension of human life that are central to her work.
Richard Leppert boldly examines the social meanings of music as these have been shaped not only by hearing but also by seeing music in performance. His purview is the northern European bourgeoisie, principally in England and the Low Countries, from 1600 to 1900. And his particular interest is the relation of music to the human body. He argues that musical practices, invariably linked to the body, are inseparable from the prevailing discourses of power, knowledge, identity, desire, and sexuality. With the support of 100 illustrations, Leppert addresses music and the production of racism, the hoarding of musical sound in a culture of scarcity, musical consumption and the policing of gender, the domestic piano and misogyny, music and male anxiety, and the social silencing of music. His unexpected yoking of musicology and art history, in particular his original insights into the relationships between music, visual representation, and the history of the body, make exciting reading for scholars, students, and all those interested in society and the arts.