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As our world advances in the fields of communication, transportation, and commerce, among others, it becomes smaller, more interlinked and interdependent as well. Geographical borders have hardly any power in controlling the flow of information and ideas. However, it is not only good ideas that are crossing borders, but also challenges and conflicts. Such factors require higher forms of cooperation and communication among governments, institutions, and people. Together with cooperation and communication come agreements and disagreements, and the development of methods that can be used in reaching such agreements – and overcoming disagreements
This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.
Contains entries that provide information about significant people, places, and events in the history of the Middle East and North Africa since 1800; arranged alphabetically from Shammar to Zurayk, with maps, genealogies, a glossary, and an index.
An introduction to the emerging field of cancer physics, integrating cancer biology with approaches from theoretical and applied physics.
The definitive treatment textbook in psychiatry, this fifth edition of Gabbard's Treatments of Psychiatric Disorders has been thoroughly restructured to reflect the new DSM-5® categories, preserving its value as a state-of-the-art resource and increasing its utility in the field. The editors have produced a volume that is both comprehensive and concise, meeting the needs of clinicians who prefer a single, user-friendly volume. In the service of brevity, the book focuses on treatment over diagnostic considerations, and addresses both empirically-validated treatments and accumulated clinical wisdom where research is lacking. Noteworthy features include the following: Content is organized acco...
This book presents strategies for analyzing qualitative and mixed methods data with MAXQDA software, and provides guidance on implementing a variety of research methods and approaches, e.g. grounded theory, discourse analysis and qualitative content analysis, using the software. In addition, it explains specific topics, such as transcription, building a coding frame, visualization, analysis of videos, concept maps, group comparisons and the creation of literature reviews. The book is intended for masters and PhD students as well as researchers and practitioners dealing with qualitative data in various disciplines, including the educational and social sciences, psychology, public health, business or economics.
Volume 35 proves to be essential reading for anyone interested in reactions between retinoid signaling pathways and the genes regulating cell proliferation/survival, developmentally-regulated changes in the nuclear envelope, the developmental roles of the EGFR, or ErbB family, the correspondence between phylogeny and life history in polyembryonic insect development, control of cadherin function by extracellular signals, the importance of the Spemann organizer for neural induction, and the study of signal transduction in Drosophila melanogaster.