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Frontiers in Anti-Cancer Drug Discovery, Volume (1)
"Frontiers in Anti-Cancer Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug di
The Physics of Cancer
An introduction to the emerging field of cancer physics, integrating cancer biology with approaches from theoretical and applied physics.
Principles of Stem Cell Biology and Cancer
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem C...
Stem Cells and Cancer
Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells—and not the major bulk of the tissue—that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy. The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.
A Critical and Historical Corpus of Florentine Painting
This new volume proposes, in similar format but with recent photographs, illustrating the painting in their present state, the new edition of the book dedicated by Richard Offner in 1947 to the workshop of Bernardo Daddi, artist very much in demand in the first half of the 14th century. To some 70 pictures catalogued by Offner with entries which are now updated with new data on state and history as well as with bibliography, ten further, hitherto unpublished or little known items are given in this edition. The survey offered here makes the circle of Daddi, where several of chief figures of the Florentine painting in the second half of the Trecento were formed, one of the better known areas of the history of Italian painting of the Middle Age and early Renaissance.
Programmable Matter
What Is Programmable Matter Programmable matter is matter which has the ability to change its physical properties in a programmable fashion, based upon user input or autonomous sensing. Programmable matter is thus linked to the concept of a material which inherently has the ability to perform information processing. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Programmable matter Chapter 2: Metamaterial Chapter 3: Electropermanent magnet Chapter 4: Self-reconfiguring modular robot Chapter 5: Claytronics Chapter 6: Cellular automaton Chapter 7: Quantum well Chapter 8: Synthetic biology (II) Answering the public top questions about programmable matter. (III) Real world examples for the usage of programmable matter in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of programmable matter' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of programmable matter.
Cancer Stem Cells
Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.
High-Risk Cutaneous Squamous Cell Carcinoma
This book is a cutting-edge resource that provides clinicians with the up-to-date practical knowledge required in order to manage SCC patients optimally. It summarizes newly available information relating to the definition of high-risk SCC, its pathophysiologic underpinnings, and its management. New prognostic information and staging systems are summarized that enable high-risk tumors to be defined more precisely than ever before. Many helpful tips are provided on the practical management of challenging cases, including multiple tumors/field cancerization, high-risk tumors, nodal metastases, and unresectable disease. The authors are all acknowledged experts in the emerging field of high-risk and advanced SCC.
