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The Brain-Dead Organ Donor
Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death. That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models. This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic ‘st...
Cardiothoracic Surgery Review
Cardiothoracic Surgery Review covers all of the core knowledge necessary to pass the cardiothoracic boards or the cardiothoracic recertification exam. Each topic presents core information in two-to-four pages and concludes with a brief list of the most important references. The topics cover all areas in cardiothoracic surgery, including cardiac surgery, pediatric cardiac surgery, and thoracic surgery. Included with the book is a companion website featuring the fully searchable text and over 60 procedural videos. This topic-based review is ideal for anyone needing to rapidly reference an up-to-date knowledge base in cardiothoracic surgery, including cardiothoracic fellows, practitioners studying for recertification, and surgical nurses.
The Heartbeat of Innovation
Great innovations take place within great institutions. Founded in 1819, Toronto General Hospital (TGH) is one of Canada’s oldest hospitals and has created a nurturing environment for early Canadian innovations in heart surgery. The Heartbeat of Innovation tells the story of the brilliant surgeons who worked there and the hospital environment that provided an incubator to the many people – skilled perfusionists, dedicated nurses, and pioneering cardiologists – who participated in the revolution in heart surgery that took place along University Avenue in Toronto. Supported by historical records, hospital archives, personal memoirs, and interviews, this book is an extensive and descripti...
Partnership for Excellence
In Partnership for Excellence, senior medical historian and award-winning author Edward Shorter details the Faculty of Medicine's history from its inception as a small provincial school to its present day status as an international powerhouse.
Organ Repair and Regeneration
Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation.
Hospital, Heal Thyself
Proven solutions to transform a healthcare system in crisis Part biography and part clear-eyed examination of a healthcare system in crisis, Hospital, Heal Thyself: One Brilliant Mathematician's Proven Plan for Saving Hospital, Many Lives. and Billions of Dollars tells the story of enigmatic healthcare visionary Eugene Litvak, whose research and strategies have already been implemented at many top 12-ranked hospitals to save hundreds of millions of dollars and countless thousands of patient lives. While U.S. healthcare costs continue to skyrocket, Litvak's program described in this book offers tested, effective methods to trim those costs while simultaneously improving patient outcomes. Writ...
Gene Delivery Systems
This unique volume in our Drugs and Pharmaceutical Sciences series covers the development of gene therapy today, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of the CRISPR/Cas9 gene-editing technique which has revolutionized genome editing and which was awarded the 2020 Nobel Prize in Chemistry. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases. Key Features: Overview of the development of gene therapy Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing Presents CRISPR gene therapy recent trends and applications Discusses siRNA, mRNA, and DNA plasmids
Difficult Decisions in Thoracic Surgery
This book describes the recommended ideal approach, rather than customary care, in selected clinical situations. Brief chapters are devoted to a specific question or decision in general thoracic surgery that is difficult or controversial. The chapters contain both evidence-based recommendations and descriptions of surgeons’ personal practices. Chapters are organized around clearly identified recommendations, making possible the identification of useful material at a glance. Over 50 different topics are presented. This book is a valuable reference source for practicing surgeons, surgeons in training, and educators.
Management of Intra-operative Crises, An Issue of Thoracic Surgery Clinics
Management of Intra-operative Crises is reviewed extensively in this important Thoracic Surgery Clinics of North America issue. Articles include: Massive Airway Hemorrhage; Great Vessel Injury; Endotracheal Tube Management and Obstructed Airway; Perioperative or Operative Pulmonary Embolus; Acute Intraoperative Aspiration; Patent Mammary Disruption During Thoracic Surgery; Immediate Post-lobectomy Crisis Management; Cardiopulmonary Bypass, Rapid Pacing, and ECMO for Emergent Intraoperative Thoracic Situations; Unexplained Intraoperative Hypotension; Coagulopathy & Anticoagulation during Thoracic Surgery; Perioperative Pneumonectomy Management; Pulmonary Artery Bleeding during VATS; Tracheal Repair and Airway Management; and more!
