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Environmentally Responsible Supply Chains
This book highlights what it takes to be successful in identifying and executing environmental responsibility from an operational perspective. It provides cutting-edge research from globally recognized field experts. It is a useful resource for practitioners to explore why and how firms engage in environmentally responsible operations, but also a valuable resource for academics as an introductory reference that provides direct exposure to key environmental operational problems faced by many firms today. This book can also be used as an introductory reading for students with varying educational backgrounds - from business school students interested in environmental issues to environmental sci...
Molecular Parasitology
In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on “the molecules” of protozoan parasites – on their genomes, proteomes, glycomes and lipidomes.
Leishmaniasis: From Innate and Adaptive Immunity to Vaccine Development
The parasitic disease leishmaniasis in its various clinical manifestations from self-resolving skin lesion to deadly systemic infection is a serious health problem in many developing countries and is considered to be a neglected tropical disease by the World Health Organization. To date, a vaccine is lacking and strategies to treat severe forms of leishmaniasis efficiently are missing. Basic research using animal models of experimental visceral or cutaneous leishmaniasis has allowed to dissect the immune response to parasitic pathogens and has contributed substantially to many important, paradigm-changing insights such as the role of cytokines in helper T-cell differentiation and the impact ...
Knowledge and Systems Sciences
This book constitutes the proceedings of the 22nd International Symposium, KSS 2023, held in Guangzhou, China, during December 2–3, 2023. The 20 full papers included in this volume were carefully reviewed and selected from 56 submissions. The volume is divided in topical sections that cover the following topics: data mining and machine learning, complex systems modeling, decision analysis and knowledge management, opinion mining and knowledge technologies.
Proceedings of the Fifteenth International Conference on Management Science and Engineering Management
This book gathers the proceedings of the fifteenth International Conference on Management Science and Engineering Management (ICMSEM 2021) held on August 1-4, 2021, at the University of Castilla-La Mancha (UCLM), Toledo, Spain. The proceedings contains theoretical and practical research of decision support systems, complex systems, empirical studies, sustainable development, project management, and operation optimization, showing advanced management concepts and demonstrates substantial interdisciplinary developments in MSEM methods and practical applications. It allows researchers and practitioners in management science and engineering management (MSEM) to share their latest insights and contribution. Meanwhile, it appeals to readers interested in these areas, especially those looking for new ideas and research directions.
Natural Small Molecule Drugs from Plants
This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.
