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Systems Biology of Cancer
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Probiotics in Anticancer Immunity
Probiotics have been suggested to be involved in both prevention and treatment of various human cancers. Probiotics in Anticancer Immunity explains biochemical mechanisms of anticancer immunity exerted by probiotics in various human cancers. It presents edited chapters focused on the evidence of probiotic use against human cancers through several animal and human studies. Part 1 of Probiotics in Anticancer Immunity consists of 11 chapters. The introductory chapters provide information about the link between gut microbiota and the host immune system in cancer and the general mechanisms of anticancer immunity exerted by probiotics. Subsequent chapters are focused on probiotics’ anticancer im...
Anticancer Immunity: Reviewing the Potential of Probiotics
Probiotics have been suggested to be involved in both prevention and treatment of various human cancers. Anticancer Immunity: Reviewing the Potential of Probiotics explains biochemical mechanisms of anticancer immunity exerted by probiotics in various human cancers. It presents edited chapters focused on the evidence of probiotic use against human cancers through several animal and human studies. This volume consists of 11 chapters. The volume continues from the previous entry with chapters focused on probiotics’ anticancer immunity in specific cancers such as, bladder cancer, renal cell carcinoma, prostate cancer, lymphomas, pancreatic cancer, oral cancer and oropharyngeal cancers. The bo...
Engineering the Plant Factory for the Production of Biologics and Small-Molecule Medicines
Plant gene transfer achieved in the early ‘80s paved the way for the exploitation of the potential of gene engineering to add novel agronomic traits and/or to design plants as factories for high added value molecules. For this latter area of research, the term "Molecular Farming" was coined in reference to agricultural applications in that major crops like maize and tobacco were originally used basically for pharma applications. The concept of the “green biofactory” implies different advantages over the typical cell factories based on animal cell or microbial cultures already when considering the investment and managing costs of fermenters. Although yield, stability, and quality of the...
Apoptosis in Health and Disease - Part A
Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. A vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target this cell death process. These two thematic volumes 125 and 126 of the Advances in Protein Chemistry and Structural Biology focus on apoptotic responses in numerous conditions - from bacterial and parasite infections to pathological states such as oxidative stress, pulmonary hypertension, different cancer types, etc. Finally, therapeutic strategies for targeting apoptosis are also discussed. - Integrates experimental and computational methods for studying apoptosis in health and different diseases, strategies for identification of suitable therapeutic targets, and design of treatments targeting key points in apoptotic cascade
3D Bioprinting in Cancer Applications
3D bioprinting in Cancer Applications is an all-encompassing guide covering both fundamentals concerning biofabrication principles and intricate protocols for precise construction of biomimetric 3D systems supporting advanced cell culture development that faithfully recapitulates human disease hallmarks, with a special focus on cancer. This title fills the void left by existing publications overlooking essential aspects associated with combining multimodal medical imaging alongside precision cancer treatment options. In 12 chapters 3D bioprinting in cancer applications leads the reader from an introduction to bioprinting technologies for cancer models, to models for immunotherapy and tumour-immune interaction, to biomimetrics 3D models to the applications of all these models in 3D bioprinted cancer models . 3D bioprinting in cancer applications uniquely combines distinct modalities under a unified framework suitable not only for seasoned veterans but also newly minted trainees encountering these sophisticated practices for the first time.
Decellularized Materials
This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.
